Eclipta alba L. Derived Phytochemicals against Campylobacter Causing Diarrhea
Sanchayita Nayak
Centurion University of Technology and Management, Odisha, India.
Subhashree Sahu
Centurion University of Technology and Management, Odisha, India.
Mukesh Kumar Biswal
Centurion University of Technology and Management, Odisha, India.
Sonali Dash
Centurion University of Technology and Management, Odisha, India.
Sagarika Parida
Centurion University of Technology and Management, Odisha, India.
Sabita Pattanayak *
Centurion University of Technology and Management, Odisha, India.
*Author to whom correspondence should be addressed.
Abstract
Phytochemicals from Eclipta alba L. plant extract are traditionally used to cure Diarrhea. It is caused by Campylobacter. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDocker energy and -CDocker interaction energy” suggested that 6, 10, 14-trimethyl-2-pentadecanone can effectively deactivate the Argininedecarboxylase enzyme (protein database code 3N29) thereby interrupting the life cycle of the organism.
Keywords: Phytochemical, Eclipta alba L., campylobacter, diarrhea