Coffea arabica L. Derived Phytochemicals against Haemophilus influenza Causing Conjunctivitis
Sutapa Nayak
Centurion University of Technology and Management, Odisha, India.
Elora Barik
Centurion University of Technology and Management, Odisha, India.
Biren Pattanayak
Centurion University of Technology and Management, Odisha, India.
Sitaram Swain
Centurion University of Technology and Management, Odisha, India.
Dipankar Bhattacharyay *
Centurion University of Technology and Management, Odisha, India and Go to Market Laboratory, Gram Tarang, Odisha, India.
*Author to whom correspondence should be addressed.
Abstract
Phytochemicals from Coffea arabica plant extract are traditionally used to cure conjunctivitis. It is caused by Haemophilus influenza. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that caffeine and chlorogenic acid can efficiently deactivate the shikimate dehydrogenase enzyme which will result in interruption of the life cycle of the microorganism.
Keywords: Phytochemical, Coffea arabica L., Haemophilus influenza