Cardamom Derived Phytochemicals against Mycobacterium tuberculosis Causing Tuberculosis
Bijan Pumar Patra
Centurion University of Technology and Management, Odisha, India.
Bapujee Palai
Centurion University of Technology and Management, Odisha, India.
Sarthak Siddhant Mishra
Centurion University of Technology and Management, Odisha, India.
Sunil Jha
Centurion University of Technology and Management, Odisha, India.
Dipankar Bhattacharyay *
Centurion University of Technology and Management, Odisha, India. and Go to Market Laboratory, Gram Tarang, Odisha, India.
*Author to whom correspondence should be addressed.
Abstract
Tuberculosis is a disease caused by severe infections by Mycobacterium tuberculosis, a pathogenic bacteria. These bacteria cause infections in humans and thus lead to an unhealthy life. Phytochemicals from cardamom plant extract are traditionally used to cure Tuberculosis. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that acetic acid can effectively deactivate histidinol dehydrogenase (H37Rv) thereby interrupting the life cycle of the organism.
Keywords: Phytochemical, cardamom, Mycobacterium tuberculosis