Piper nigrum Derived Phytochemicals against Gonorrhoea
Sharbani Bahali
Centurion University of Technology and Management, Odisha, India.
Debasmita Das
Centurion University of Technology and Management, Odisha, India.
Sunanya Das
Centurion University of Technology and Management, Odisha, India.
Sitaram Swain
Centurion University of Technology and Management, Odisha, India.
G. K. Panigrahi
Centurion University of Technology and Management, Odisha, India.
Dipankar Bhattacharyay *
Centurion University of Technology and Management, Odisha, India. and Go to Market Laboratory, Gram Tarang, Odisha, India.
*Author to whom correspondence should be addressed.
Abstract
Phytochemicals from Piper nigrum plant extract are traditionally used to cure Gonorrhoea. It is caused by Neisseria gonnorrhoeae. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that p-cymenecan effectively deactivate the dihydrofolate reductase enzyme thereby interrupting the life cycle of the organism.
Keywords: Phytochemical, Piper nigrum, Neisseria gonnorrhoeae