A Comparative Study on Antioxidation and Antibacterial Activities Triphala Herb Extracts from Chae Son, Lampang, Thailand
Wilart Pompimon *
Faculty of Science, Lampang Rajabhat University, 52100 Lampang, Thailand.
Wipanoot Baison
Faculty of Science, Lampang Rajabhat University, 52100 Lampang, Thailand.
Angkhana Chuajedton
Faculty of Science, Lampang Rajabhat University, 52100 Lampang, Thailand.
Phansuang Udomputtimekakul
Faculty of Science, Lampang Rajabhat University, 52100 Lampang, Thailand.
Punchavee Sombutsiri
Faculty of Science, Lampang Rajabhat University, 52100 Lampang, Thailand.
Boonthawan Wingwon
Faculty of Management Science, Lampang Rajabhat University, 52100 Lampang, Thailand.
Chatchanok Udomtanakunchai
Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, 53000 Chiang Mai, Thailand.
*Author to whom correspondence should be addressed.
Abstract
Introduction: Triphala, a herbal medicine which is a product from Chae Son, Lampang, Thailand, is an unequal-proportional mixture of fruits of three herbs, Phyllanthus emblica, Terminalia chebula, and Terminalia bellirica (2:1:1).
Materials and Methods: The contemporary study concentrated on extracts detection and comparative analysis between various annual year (A.D.2017/2018) activities in hexane, ethyl acetate, and methanolic extracts of Triphala. The determination of antioxidant was using by 1,1-diphenyl-2-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP). The broth dilution and agar well diffusion assay were determined antibacterial.
Results: Results exposed the valuable biological activity extracts from ethyl acetate and methanol solvents of T. chebula and T. bellirica, which strength is accountable for biological activities. Extracts displayed acceptable radical-scavenging activity analogous with ascorbic acid. The methanol extract of T. bellirica (0.0013 mg/mL), ethyl acetate extract of P. emblica (0.0009 mg/mL), in A.D. 2017 and the ethyl acetate extract of P. emblica (0.0090 mg/mL), the methanol extract of Triphala (0.0176 mg/mL) in 2018, were exhibited higher antioxidant activity. Also, extracts indicated hopeful antibacterial potential against tested strain comparable to chloramphenicol.
Conclusion: The results in A.D. 2017 showed that inhibition zone of P. emblica in ethyl acetate extract; S. aureas (8.67 mm), E. aerogenes (8.67 mm), E. coli (EPEC) (7.67 mm), P. mirabilis (7.73 mm) , S. typhimurium (8.33 mm), S. flexneri (8.33 mm) and V. cholera (7.33 mm) together with P. emblica methanol extract; S. aureas (6.67 mm), E. aerogenes (7.76 mm.) and V. cholera (4.0 mm). Therefore, it could be concluded that Triphala may be a talented candidate in pharmaceutical and future medicine.
Keywords: Triphala, Phyllanthus emblica, Terminalia chebula, Terminalia bellirica.