https://journaljpri.com/index.php/JPRI <p style="text-align: justify;"><strong>Journal of Pharmaceutical Research International (ISSN: 2456-9119)</strong> is dedicated to publish high quality papers (<a href="https://journaljpri.com/index.php/JPRI/general-guideline-for-authors">Click here for Types of paper</a>) in all areas of pharmaceutical Science including pharmaceutical drugs, community pharmacy, hospital pharmacy, clinical pharmacy, compounding pharmacy, consultant pharmacy, internet pharmacy, veterinary pharmacy, nuclear pharmacy, military pharmacy, pharmacy informatics, pharmaceutics, medicinal chemistry, pharmacognosy, pharmacotherapy, pharmacodynamics, pharmacokinetics, clinical pharmacology, neuropharmacology, psychopharmacology, pharmacogenetics, pharmacogenomics, pharmacoepidemiology, toxicology, theoretical pharmacology, posology, pharmacognosy, behavioral pharmacology, environmental pharmacology, medicine development and safety testing, drug legislation and safety, pharmaceutical microbiology, pharmaceutical molecular biology, pharmaceutical biotechnology. By not excluding papers based on novelty, this journal facilitates the research and wishes to publish papers as long as they are technically correct and scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled, OPEN peer-reviewed, open-access INTERNATIONAL journal.</p> <p style="text-align: justify;">We are happy to announce that we are now a signatory and a proud member of <a href="https://journaljpri.com/index.php/JPRI/sdg-publishers-compact"><strong>SDG Publishers Compact</strong></a>, an initiative by the United Nations.</p> Journal of Pharmaceutical Research International en-US Journal of Pharmaceutical Research International 2456-9119 https://journaljpri.com/index.php/JPRI/article/view/7835 <p>Rare plant-derived polysaccharides have emerged as promising biomaterials for advanced drug delivery due to their structural adaptability and functional performance. This review critically evaluates polysaccharides from underutilized sources such as tamarind seed, fenugreek, bael fruit, jackfruit, okra, aloe, and Plantago ovata. Tamarind polysaccharide-based systems demonstrate high encapsulation efficiency (&gt;70%) and sustained drug release beyond 8–12 h with enhanced mucoadhesion and prolonged residence time. Thiolated fenugreek mucilage exhibits improved swelling and controlled release in gastroretentive formulations. Bael and jackfruit polysaccharides provide good mechanical strength and stability in matrix and nanocarrier systems. Okra-based formulations show high drug entrapment (&gt;75%) and extended release, supporting colon-targeted delivery. Aloe polysaccharide hydrogels enable sustained release and improved tissue regeneration, while Plantago ovata allows enzyme-triggered site-specific drug release. Despite these advantages, variability, limited toxicity data, and scale-up challenges hinder clinical translation. Overall, these polysaccharides offer improved functional performance over conventional polymers and require further standardization for pharmaceutical applications.</p> Antesh Kumar Jha Shiv Kumar Srivastava Mahesh Prasad Shashi Shankar Abhishek Kumar Singh Anant Prakash Pandey Copyright (c) 2026 Author(s). The licensee is the journal publisher. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 2026-04-30 2026-04-30 38 5 1 15 10.9734/jpri/2026/v38i57835