https://journaljpri.com/index.php/JPRI <p style="text-align: justify;"><strong>Journal of Pharmaceutical Research International (ISSN: 2456-9119)</strong> is dedicated to publish high quality papers (<a href="https://journaljpri.com/index.php/JPRI/general-guideline-for-authors">Click here for Types of paper</a>) in all areas of pharmaceutical Science including pharmaceutical drugs, community pharmacy, hospital pharmacy, clinical pharmacy, compounding pharmacy, consultant pharmacy, internet pharmacy, veterinary pharmacy, nuclear pharmacy, military pharmacy, pharmacy informatics, pharmaceutics, medicinal chemistry, pharmacognosy, pharmacotherapy, pharmacodynamics, pharmacokinetics, clinical pharmacology, neuropharmacology, psychopharmacology, pharmacogenetics, pharmacogenomics, pharmacoepidemiology, toxicology, theoretical pharmacology, posology, pharmacognosy, behavioral pharmacology, environmental pharmacology, medicine development and safety testing, drug legislation and safety, pharmaceutical microbiology, pharmaceutical molecular biology, pharmaceutical biotechnology. By not excluding papers based on novelty, this journal facilitates the research and wishes to publish papers as long as they are technically correct and scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled, OPEN peer-reviewed, open-access INTERNATIONAL journal.</p> <p style="text-align: justify;">We are happy to announce that we are now a signatory and a proud member of <a href="https://journaljpri.com/index.php/JPRI/sdg-publishers-compact"><strong>SDG Publishers Compact</strong></a>, an initiative by the United Nations.</p> Journal of Pharmaceutical Research International en-US Journal of Pharmaceutical Research International 2456-9119 https://journaljpri.com/index.php/JPRI/article/view/7809 <p>Food science has seen a revolution because of nanotechnology, which uses materials at the nanoscale to improve quality, safety, and usefulness. With sizes ranging from 1 to 100 nm, nanoparticles (NPs) have special physical and chemical characteristics that set them apart from their bulk counterparts. These substances are used in packaging for antibacterial and preservation reasons, as well as in food systems to enhance texture, stability, colour, and nutrition delivery. However, there are serious safety and toxicological issues, frame work and risk Factors with the increasing use of engineered nanomaterials (ENMs) in food and feed items. Both inorganic (like silver, titanium dioxide, iron oxide, and zinc oxide) and organic (like lipid, protein, and carbohydrate- based nanoparticles) food-related nanoparticles are classified in this review, along with their fate and possible toxicity in the gastrointestinal tract (GIT). Organic nanoparticles are often less harmful because of enzymatic breakdown, whereas inorganic nanoparticles have demonstrated variable levels of accumulation and organ toxicity based on size, solubility, and reactivity. Limited and contradictory toxicological data highlight the urgent need for thorough long-term studies on nanoparticle exposure through diet, medicines, despite promised functional improvements. The fast-developing nano-enabled food technology and feed, it is crucial to comprehend the risk factors, the nanoparticles interact with biological systems in order to create appropriate regulatory frameworks and guarantee consumer safety.</p> Basanta Kumar Panigrahi Manojit Pal Siba Prasad Mishra Copyright (c) 2026 Author(s). The licensee is the journal publisher. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 2026-01-28 2026-01-28 38 2 1 17 10.9734/jpri/2026/v38i27809