Overview and Future Perspectives on Bone 3D Bioprinting
Claudia Todaro
Department of Clinical Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
Mirko Torchia
Department of Clinical Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
Marco Benazzo
Department of Clinical Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
Ruggero Rodriguez y Baena
Department of Clinical Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
Pietro Canzi
Department of Clinical Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
Saturnino Marco Lupi *
Department of Clinical Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
*Author to whom correspondence should be addressed.
Abstract
3D bioprinting is a prominent topic in the field of tissue engineering. The progress made in the last decade is remarkable, but the technology still shows many drawbacks and limitations due to the relatively short introduction. In this paper we summarize the major 3D bioprinting protocols such as material jetting, material extrusion, and vat polymerization, highlighting the pros and cons of each technology, then we analyze different biomaterials and various components of the bio-inks compatible with the available 3D bioprinters. The goal of this review is to examine the existing tools to produce bone scaffolds and highlight future developments in the field of Guided Bone Regeneration (GBR) inside the oral cavity.
Keywords: Bioprinting, 3D printing, dentistry, bone tissue engineering