A Review of the State of the Art towards Biological Applications of Graphene-based Nanomaterials

Varun Kumar Sharma

Department of Natural and Applied Sciences, School of Science and Technology, The Glocal University, Mirzapur Pole, Saharanpur, Uttar Pradesh- 247121, India.

Mohd Yusuf *

Department of Natural and Applied Sciences, School of Science and Technology, The Glocal University, Mirzapur Pole, Saharanpur, Uttar Pradesh- 247121, India.

Prem Kumar

ECE Department, The Glocal University, Mirzapur Pole, Saharanpur, Uttar Pradesh- 247121, India.

. Sheeba

ECE Department, The Glocal University, Mirzapur Pole, Saharanpur, Uttar Pradesh- 247121, India.

. Nafisa

Department of Natural and Applied Sciences, School of Science and Technology, The Glocal University, Mirzapur Pole, Saharanpur, Uttar Pradesh- 247121, India.

Munesh Sharma *

Department of Chemistry, JV College (Affiliated to CCS University Meerut), Baraut, Baghpat Uttar Pradesh- 250611, India.

Vipan Chand Waila

Department of Natural and Applied Sciences, School of Science and Technology, The Glocal University, Mirzapur Pole, Saharanpur, Uttar Pradesh- 247121, India.

Shafat Ahmad Khan

Department of Chemistry, School of Basic and Applied Sciences, Galgotias University, Greater Noida, Uttar Pradesh- 203201, India.

Nizamul Haque Ansari

Department of Physical Sciences, Sant Baba Bhag Singh University, Jalandhar, Punjab 144030, India.

Saifullah Zaphar

Department of Mechanical Engineering, The Glocal University, Mirzapur Pole, Saharanpur, Uttar Pradesh- 247121, India.

. Sadiya

Department of Natural and Applied Sciences, School of Science and Technology, The Glocal University, Mirzapur Pole, Saharanpur, Uttar Pradesh- 247121, India.

*Author to whom correspondence should be addressed.


Abstract

The field of nanoscience has evolved into a wide variety of successes over the past two decades and the emphasis on nanotechnology is to revolve around various dynamic fields, such as sensor, biomedical, and many useful applications. Advances in related fields are certainly due to the ability to synthesize nanoparticles from a variety of materials, structures, and to convert samples into complex nanoarchitectures. The promises of nanomedicine are broad. Graphene (Gr), the first 2-dimensional material to stand alone, is a type of new nanomaterial that leads to the excitement of natural biological applications. Number of researches has been conducted on applicability of GBNs in the area of environment, biomedical, and healthcare sectors. As compared to other nanomaterials, extraordinary properties of graphene-based nanomaterials (GBNs) like high surface area, multilayers, multifunctional and excellent biocompatibility make them capable to play great roll of highly-tailored multifunctional delivery vehicles for drugs delivery, gene delivery, phototherapy and bioimaging. However, research communities performed plenty of research works on GBNs synthesis and biological acitivity evaluation, but  there is limited comprehensive reviews published so far biological applications. So, we have studied a large number of scientific reports and investigations, presented in this review describing recent progress and modern perspectives with respect to graphene and related nanomaterials for biological applications.

Keywords: Graphene, drug delivery, tissue engineering, nanomedicine, biomedical applications


How to Cite

Sharma, V. K., Yusuf, M., Kumar, P., Sheeba, ., Nafisa, ., Sharma, M., Waila, V. C., Khan, S. A., Ansari, N. H., Zaphar, S. and Sadiya, . (2021) “A Review of the State of the Art towards Biological Applications of Graphene-based Nanomaterials”, Journal of Pharmaceutical Research International, 33(55B), pp. 216–230. doi: 10.9734/jpri/2021/v33i55B33869.

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