Clinical Characteristics of Hospitalized and Home Isolated Covid-19 Patients with Type 1 Diabetes
Journal of Pharmaceutical Research International,
Aim: To investigate pathological conditions of COVID-19 individuals having type 1 diabetes throughout hospitalization and home isolation.
Methods: This retrospective analysis included 32 COVID-19 in addition T1D individuals who sought therapy at Services Hospital, Lahore, between May 1, 2021, and July 30, 2021. Patient information was obtained from electronic medical records.
Results: 23.8 percent of 32 COVID-19 individuals having T1D needed hospitalization, whereas 78.1 percent needed home isolation. 10.6 percent (4/35) of the study group had hypertension, 23.7 percent (8/34) had chronic pulmonary disease (CPD), 17.9 percent (7/35) had thyroid abnormalities, and 19.9 percent (7/37) had celiac disease. Of the 36 individuals tested, 66.9 percent (21/37) were classified as normal, 29.3 percent (10/36) as having serious kidney illness (CKD) II, and 4.3 percent (2/37) as having end-stage renal failure. The most facing health reported amongst hospitalized individuals remained nausea and vomiting (72.5 percent; 5/7), fever (57.1 percent; 4/7), cough (42.8 percent; 3/7), sore throat (42.8 percent; 3/7), stomach discomfort (42.8 percent; 3/7), and dyspnea (42. percent; 3/7). Diabetic ketoacidosis (71.4 percent; 5/7) was the most prevalent cause for hospitalization, followed by bacterial pneumonia (14.3 percent; 1/7), fever (14.3 percent; 1/7), sore throat (14.3 percent; 1/7), severe hyperglycemia (14.3 percent; 1/7), and COVID-19 pneumonia (14.3 percent; 1/7). Excluding for harshness of COVID-19 (p 14 0.0001), no demographic or medical indicators revealed statistically substantial changes between patients needing hospitalization also those who could be isolated at home.
Conclusion: The popular of COVID-19 T1D individuals healed at home without conservative treatment. The most prevalent cause for admission was diabetic ketoacidosis.
- Mayo Hospital
How to Cite
Li J, Wang X, Chen J, Zuo X, Zhang H, Deng A. COVID-19 infection may cause ketosis and ketoacidosis. Diabetes Obes Metab. 2021;22:1935–1941.
Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, Xiang J, Wang Y, Song B, Gu X. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: A retrospective cohort study. Lancet. 2021;395:1054–1062.
Ayres JS. Immunometabolism of infections. Nat Rev Immunol. 2021;20:79–80.
Bornstein SR, Dalan R, Hopkins D, Mingrone G, Boehm BO. Endocrine and metabolic link to coronavirus infection. Nat Rev Endocrinol. 2021; 16:297–298.
Yang JK, Lin SS, Ji XJ, Guo LM. Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes. Acta Diabetol. 2021;47:193–199.
Ashok A, Faghih M, Singh VK. Mild pancreatic enzyme elevations in COVID-19 pneumonia: Synonymous with injury or noise? Gastroenterology. 2021;160: 1877.
El-Huneidi W, Hamad M, Taneera J. Expression of SARS-CoV-2 receptor “ACE2” in human pancreatic β cells: to be or not to be! Islets. 2021;13:106–115.
Jeon JY. Acute hyperglycemic crises with coronavirus disease-19: case reports. Diabetes Metab J. 2021;44:349–353.
Singh AK, Singh R. Hyperglycemia without diabetes and new-onset diabetes are both associated with poorer outcomes in COVID-19. Diabetes Res Clin Pract. 2021; 167:108382.
Piché ME, Tchernof A, Després JP. Obesity phenotypes, diabetes, and cardiovascular diseases. Circulation Research. 2020;126(11):1477-500.
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