A Bone Marrow Aspiration Study in Evaluation of Severe Anemia in Adults
Journal of Pharmaceutical Research International,
Page 33-43
DOI:
10.9734/jpri/2021/v33i23B31419
Abstract
Anemia is a global health challenge and is the most significant health problem encountered in the developing countries especially in India. According to the World Health Organisation (WHO), 1.62 million !! billion people per year are affected globally with anemia which constitutes 24.8% of the world population. To evaluate the clinical presenting features and the basic haematological parameters in adult patients with severe anemia, the morphological alterations of Bone marrow aspirates in these patients were studied. To correlate these morphological alterations of Bone marrow aspirates with the clinical and the basic haematological parameters in severe anemia.
Keywords:
- Anemia
- bone marrow
- haematological
How to Cite
Sithika, T. A., Prasaad, P. R. and Sivastava, V. (2021) “A Bone Marrow Aspiration Study in Evaluation of Severe Anemia in Adults”, Journal of Pharmaceutical Research International, 33(23B), pp. 33-43. doi: 10.9734/jpri/2021/v33i23B31419.
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Ekwere TA, Ino-Ekanem MB, Motilewa O . Indications and Spectrum of Hematological Disorders from Bone Marrow Aspiration Examination: A Three Year Review Study. Global Journal of Hematology and Blood Transfusion. 2015;2:4-8.
Reddy PN and Swami V. Clinical hematological and bone marrow study of severe anaemia. Indian Journal of Basic and Applied Medical Research. 2015;4(2):292-297.
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Elis A, Ravid M, Manor Y, Bental T, Lishner M. A clinical approach to Idiopathic Normocytic-Normochromic Anemia?” J Am Geriatr Soc. 1996;44:832-4.
Chattopadhyay D, Adhya S. Prevalence of Anaemia among OPD Patients of a Tertiary Care Hospital of Eastern India. IOSR Journal of Dental and Medical Sciences. 2013;10(6):01-03.
Alvarez-Uria G, Naik PK, Midde M, Yalla PS, Pakam R. Prevalence and severity of anaemia stratified by age and gender in rural India. Anaemia. 2014;2014: 1-5.
Sgnaolin V, Engroff P, Ely LS, Schneider RH, Schwanke CH, Gomes I et al. Hematological parameters and prevalence of anemia among free-living elderly in south Brazil. Rev. Bras. Hematol. Hemoter. 2013;35(2):115-118.
Choudhary TS, Kochar SK. Clinical and hematological profile of severe anaemia. JAPI. 1999;2:85-87.
Mahajan SK, Aundhakar SC. A study of the prevalence of serum vitamin B12 and folic Acid deficiency in Western maharashtra. J Family Med Prim Care. 2015;4(1):64-8.
Olivares M, Hertramp E, Capurro MT, Wegner D. Prevalence of anemia in elderly subjects living at home: role of micronutrient deficiency and inflammation. Eur J Clin Nutr. 2000;54(11):834-9.
Bucker M, Audu BM, Sadauki HM, Elnafaty AU, Mairiga AG. Prevalence of Iron deficiency and Megaloblstic anemia at Booking in a Secondary health facility in North Eastern Nigeria. Niger Med J. 2009;50(2):4-8.
Carmel R. Anemia and aging: an overview of clinical, diagnostic and biological issues. Blood Rev.2001;15(1):9–18.
Shrivastava SR, Hippargi SB, Ambali AP, Yelikar BR. Patterns of Anemia in Geriatric Age Group. Journal of Krishna Institute of Medical Sciences University 2013;2(1):77-82.
Singla V, Bodal VK, Jassal V, Singh BM, Zakhmi S , Kanwar N, et al. Pattern of Peripheral Blood Film Findings in a Tertiary Care Centre in Punjab – A Study of 10,000 Cases. RJPBCS. 2016;7(1):455-60.
Khanduri U, Sharma A Megaloblastic Anaemia: Prevalence and Causative Factors. Natl Med J India. 2007;20(4): 172-5.
Vineetha U, Tarun Kumar D, Bhawana A, Zachariah B, Ashish K. Clinico-aetiologic profile of macrocytic anemias with special reference to megaloblastic anemia. Indian Journal of Hematology and Blood Transfusion. 2008;24(4):155-165.
Ekwere TA, Ino-Ekanem MB, Motilewa O . Indications and Spectrum of Hematological Disorders from Bone Marrow Aspiration Examination: A Three Year Review Study. Global Journal of Hematology and Blood Transfusion. 2015;2:4-8.
Reddy PN and Swami V. Clinical hematological and bone marrow study of severe anaemia. Indian Journal of Basic and Applied Medical Research. 2015;4(2):292-297.
Thiyagarajan P, Suresh TN, Anjanappa R, Harendra Kumar ML. Bone- marrow spectrum in a tertiary care hospital: Clinical indications, peripheral smear correlation and diagnostic value. Med J DY Patil Univ. 2015;8:490-4.
Adewoyin AS, Ezire ES, Adeyemi O, Idubor NT, Okiya DO. Bone marrow aspiration cytology studies in a tertiary hospital, Nigeria: A series of 88 cases. Annals of Pathology and Laboratory Medicine. 2015;2(4):108-114.
Pathak R, Jha A, Sayami G. Evaluation of bone marrow in patients with pancytopenia. Journal of Pathology of Nepal. 2012;2:265-271.
Al-Ghazaly J, Al-Selwi AH, Abdullah M, Al-Jahafi AK, Al-Dubai W, Al-Hashdi A. Pattern of Haematological Diseases Diagnosed by Bone Marrow Examination in Yemen: A Developing Country Experience. Clin Lab Haematol. 2006; 28:376-81.
Mahmood K, Siddiqi HS, Sajjad, Shoukat S, Mehmood Z, Wasim A. Iron-deficiency anemia. A study of risk factors among adult population of Quetta Valley. Health. 2012;4(9):607-611.
Ramazan M, Hayriye AK, Taner U, Melih E, Cemalettin G, Mesut E. Prevalence and etiology of anemias in the adult Turkish population. Turk J Med Sci. 2012;42(6): 957-963.
Wang X, Wu Z, Chen Y, Zhu J, Dong X, Fu C et al. Increased prevalence and incidence of anemia among adults in transforming rural China: two cross-sectional surveys. BMC Public Health. 2015;15(1):36-39.
Kumar R, Kalra SP, Kumar H, Anand AC, Madan H. Pancytopenia- A six year Study. JAPI. 2001;49:1078-1081.
Fireman, Zachlka R, Mouch SA and Kopelman Y .The Role of Endoscopy in the Evaluation of Iron Deficiency Anemia in Premenopausal Women. IMAJ. 2006;8:88-90.
Elis A, Ravid M, Manor Y, Bental T, Lishner M. A clinical approach to Idiopathic Normocytic-Normochromic Anemia?” J Am Geriatr Soc. 1996;44:832-4.
Chattopadhyay D, Adhya S. Prevalence of Anaemia among OPD Patients of a Tertiary Care Hospital of Eastern India. IOSR Journal of Dental and Medical Sciences. 2013;10(6):01-03.
Alvarez-Uria G, Naik PK, Midde M, Yalla PS, Pakam R. Prevalence and severity of anaemia stratified by age and gender in rural India. Anaemia. 2014;2014: 1-5.
Sgnaolin V, Engroff P, Ely LS, Schneider RH, Schwanke CH, Gomes I et al. Hematological parameters and prevalence of anemia among free-living elderly in south Brazil. Rev. Bras. Hematol. Hemoter. 2013;35(2):115-118.
Choudhary TS, Kochar SK. Clinical and hematological profile of severe anaemia. JAPI. 1999;2:85-87.
Mahajan SK, Aundhakar SC. A study of the prevalence of serum vitamin B12 and folic Acid deficiency in Western maharashtra. J Family Med Prim Care. 2015;4(1):64-8.
Olivares M, Hertramp E, Capurro MT, Wegner D. Prevalence of anemia in elderly subjects living at home: role of micronutrient deficiency and inflammation. Eur J Clin Nutr. 2000;54(11):834-9.
Bucker M, Audu BM, Sadauki HM, Elnafaty AU, Mairiga AG. Prevalence of Iron deficiency and Megaloblstic anemia at Booking in a Secondary health facility in North Eastern Nigeria. Niger Med J. 2009;50(2):4-8.
Carmel R. Anemia and aging: an overview of clinical, diagnostic and biological issues. Blood Rev.2001;15(1):9–18.
Shrivastava SR, Hippargi SB, Ambali AP, Yelikar BR. Patterns of Anemia in Geriatric Age Group. Journal of Krishna Institute of Medical Sciences University 2013;2(1):77-82.
Singla V, Bodal VK, Jassal V, Singh BM, Zakhmi S , Kanwar N, et al. Pattern of Peripheral Blood Film Findings in a Tertiary Care Centre in Punjab – A Study of 10,000 Cases. RJPBCS. 2016;7(1):455-60.
Khanduri U, Sharma A Megaloblastic Anaemia: Prevalence and Causative Factors. Natl Med J India. 2007;20(4): 172-5.
Vineetha U, Tarun Kumar D, Bhawana A, Zachariah B, Ashish K. Clinico-aetiologic profile of macrocytic anemias with special reference to megaloblastic anemia. Indian Journal of Hematology and Blood Transfusion. 2008;24(4):155-165.
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