The Adverse Effect of Mobile Phone Radiations on Dorsal Root Ganglion of Albino Rats
Journal of Pharmaceutical Research International,
Page 54-60
DOI:
10.9734/jpri/2021/v33i1331266
Abstract
Objectives: To assess the effect of Mobile Phone Radio Frequency Electromagnetic Radiation (RF-EMR) on the histological structure of dorsal root ganglia in albino rats.
Methods: Twenty-four albino rats divided into one control and three experimental groups were studied for four weeks. The experimental groups were exposed to three different levels of RF-EMR through complete missed calls of 80,120 and160 calls per day respectively, using a GSM mobile phone of 0.9GHz to1.8 GHz in silent mode. The dorsal root ganglia of the sacrificed Rats were examined under light and transmission electron microscope (TEM).
Results: Dorsal root ganglions of exposed rats showed considerable histological changes like reduction in cell size, condensation of cytoplasm, peripherally located heterochromatin nucleus, loss of nucleolus and densely packed myelinated nerve fibers. No such changes were observed in control rats.
Conclusion: Dorsal root ganglionic cells showed enduring and continuous changes when exposed to RF-EMR. The severity of histomorphological changes was dose-dependent, which increased constantly with radiation dosage increment. It might be fair to conclude that degenerative changes in the Dorsal Root Ganglion of the spinal cord, could be attributed to the long-term exposure to RF-EMR.
Keywords:
- Albino rats
- dorsal root ganglion
- mobile phone radiofrequency electromagnetic radiations
- spinal ganglion
- histomorphological changes.
How to Cite
References
Available:https://www.euro.who.int/document/e89486.pdf
Sanou B. ICT Facts & Figures. The world in Itu. 2015;150. [Internet]
Available:https://www.itu.int/en/ITU-D/Statistics/Documents/facts/ICTFactsFigures2015.pdf
Boice Jr JD, Tarone RE. Cell phones, cancer, and children. J Natl Cancer Inst. 2011;103(16):1211–3. [Internet]
Available:https://doi.org/10.1093/jnci/djr285
Nascimento RS, Santiago MF, Marques SA, Allodi S, Martinez AMB. Diversity among satellite glial cells in dorsal root ganglia of the rat. Brazilian J Med Biol Res. 2008;41(11):1011–7. [Internet]
Available:https://www.bjournal.org/wp-content/uploads/articles_xml/1414-431X-bjmbr-S0100-879X2008001100011/1414-431X-bjmbr-S0100-879X2008001100011.x72422.pdf
Teimori F, Khaki AA, Rajabzadeh A, Roshangar L. The effects of 30 mT electromagnetic fields on hippocampus cells of rats. Surg Neurol Int. 2016;7:70. [Internet]
Available:http://surgicalneurologyint.com/wp-content/uploads/2016/07/6791/SNI-7-70.pdf
Taufiq F, Shariff EA, Ahmad A. Effect of radiofrequency electromagnetic radiation on the spinal cord of albino rats: A neurohistological study. Saudi J Med. 2018;3(11):620–8. [Internet]
Available:http://scholarsmepub.com/wp-content/uploads/2018/12/SJM-311-620-628-final.pdf
Taufiq F, Srivastava M. Effects of Radio-Frequency Electromagnetic Radiations (RF-EMR) on Cerebellar Cortex of Albino Rats: - A Light and Electron Microscopic Study. Saudi J Med. 2018;3(3):86–94. [Internet]
Available:http://scholarsmepub.com/wp-content/uploads/2018/03/SJM-33-86-94-c.pdf
Adjene JO, Ajakaye IO, Nosakhare PO. Morphological effects of chronic efavirenz administration on the kidney of adult Wistar rats. Genomic Med Biomarkers, Heal Sci. 2011;3(2):76–80. [Internet].
Available:https://reader.elsevier.com/reader/sd/pii/S2211425411000057?token=3833DC9822FC253030CE43F9467FEF188C5A92ADB43EC6438AB087D67C0992AF13730EF6FE46C65F583D7FE0F222AAC5
Salford LG, Brun AE, Eberhardt JL, Malmgren L, Persson BRR. Nerve cell damage in mammalian brain after exposure to microwaves from GSM mobile phones. Environ Health Perspect. 2003; 111(7):881–3. [Internet]
Available:https://ehp.niehs.nih.gov/doi/pdf/10.1289/ehp.6039
Miettinen TP, Björklund M. Mitochondrial function and cell size: an allometric relationship. Trends Cell Biol. 2017;27(6): 393–402.
Dahl KN, Ribeiro AJS, Lammerding J. Nuclear shape, mechanics, and mechanotransduction. Circ Res. 2008; 102(11):1307–18. [Internet]
Available:https://www.ahajournals.org/doi/epub/10.1161/CIRCRESAHA.108.173989
Garaj-Vrhovac V, Horvat D, Koren Z. The effect of microwave radiation on the cell genome. Mutat Res Lett. 1990;243(2): 87–93.
Sarkar S, Ali S, Behari J. Effect of low power microwave on the mouse genome: a direct DNA analysis. Mutat Res Toxicol. 1994;320(1–2):141–7.
LAI H. Single-and double-strand DNA breaks in rat brain cells after acute exposure to radiofrequency electromagnetic radiation. Int J Radiat Biol. 1996;69(4):513–21.[Internet].
DOI:https://doi.org/10.1080/095530096145814
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