Preliminary Phytochemical Screening of Elytraria acaulis Roots
Journal of Pharmaceutical Research International,
Page 1-9
DOI:
10.9734/jpri/2021/v33i431165
Abstract
The main objectives of this study were to qualitatively evaluate the profile of phytochemical constituents of Elytraria acaulis root (EAR) extracts. The dried powder of the roots of the plant was extracted with three different solvents namely petroleum ether, methanol and water, and subjected to various phytochemical tests and UV-VIS spectrophotometry to ascertain the principal constituents contained in the extracts. The result revealed the presence of alkaloids, flavonoids, tannins, glycosides with various other phytoconstituents in different extracts of Elytraria acaulis roots (EAR). We suggest that various extracts of Elytraria acaulis roots (EAR) might have potential chemical constituents that could be used in the future for the development of novel therapeutic agent.
Keywords:
- Elytraria acaulis
- UV-VIS
- phytoconstituents
- flavonoids
- qualitative.
How to Cite
Singh, S., Nigam, R., Sharma, A., Kumar, A., & Laxmi, V. (2021). Preliminary Phytochemical Screening of Elytraria acaulis Roots. Journal of Pharmaceutical Research International, 33(4), 1-9. https://doi.org/10.9734/jpri/2021/v33i431165
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DOI:10.15560/12.1.1840
Reddy GV, Kumar RV, Reddy MK. Preliminary phytochemical analysis and antioxidant activity of Elytraria acaulis plant extracts. Int. J. Pharm. Sci. Rev. Res. 2015;30(1):173–176.
Babu PS, Babu KA, Chitra K, Chamundeeshwari D. A review on phytochemical and pharmacological profile of Elytraria acaulis Lindau. Int. J. Pharm. Sci. Res. 2015;6(9):3671– 3675.
DOI:10.13040/IJPSR.09758232.6(9).3671-75
Manigandan M, Kolanjinathan K. Qualitative phytochemical screening and antioxidant activity of Elytraria acaulis Lindau (Acanthaceae). Asian J. Pharm. Clin. Res. 2016;9(3):1–4.
DOI:10.22159/ajpcr.2016.v9s3.15759
Sankaranarayanan S, Bama P, Ramachandran J, Kalaichelvan PT, Deccaraman M, Vijayalakshimi M et al. Ethnobotanical study of medicinal plants used by traditional users in Villupuram district of Tamil Nadu, India. J. Med. Plants Res. 2010;4(12):1089– 1101.
DOI:10.5897/JMPR09.027
Sikarwar RLS, Kaushik JP. Traditional medicine among the rural folk of Morena district Madhya Pradesh. Anc. Sci. Life, 1992;12(1–2):274–279.
Sikarwar R, Pathak B, Jaiswal A. Some unique ethnomedicinal perceptions of tribal communities of Chitrakoot, Madhya Pradesh. Indian J. Tradit. Knowl. 2008;7(4):613–617.
Singh S, Nigam R, Sharma A, Kumar A, Laxmi V. In-vitro antibacterial activity of Elytraria acaulis roots against some gram-positive and gram-negative bacterial strains. J. Pharmacogn. Phytochem. 2020;9(5):2218–2225.
DOI:10.22271/phyto.2020.v9.i5ae.12673
Harborne AJ. Phytochemical methods a guide to modern techniques of plant analysis, 3rd ed. Springer Netherlands; 1998.
Abubakar AR, Haque M. Preparation of medicinal plants: Basic extraction and fractionation procedures for experimental purposes. J. Pharm. Bioallied Sci. 2020;12(1):1.
DOI:10.4103/jpbs.JPBS_175_19
Cowan MM. Plant products as antimicrobial agents. Clin. Microbiol. Rev. 1999;12(4):564–582.
Das K, Tiwari RKS, Shrivastava DK. Techniques for evaluation of medicinal plant products as antimicrobial agent: Current methods and future trends. J Med Plants Res, 2011;10(4):104–11.
Dai J, Mumper RJ. Plant phenolics: Extraction, analysis and their antioxidant and anticancer properties. Molecules, 2010;15(10):7313–7352.
DOI:10.3390/molecules15107313
Soobrattee MA, Neergheen VS, Luximon-Ramma A, Aruoma OI, Bahorun T. Phenolics as potential antioxidant therapeutic agents: Mechanism and actions. Mutat. Res. 2005;579(1–2):200–213.
DOI:10.1016/j.mrfmmm.2005.03.023
Panche AN, Diwan AD, Chandra SR. Flavonoids: An overview. J. Nutr. Sci. 2016;5(E47):1-15.
DOI:10.1017/jns.2016.41
Al-Dosary DI, Alhomida AS, Ola MS. Protective effects of dietary flavonoids in diabetic induced retinal neurodegeneration. Curr. Drug Targets 2017;18(13):1468–1476.
DOI:10.2174/1389450117666161003121304.
Ashok PK. Tannins are astringent. J Pharmacogn Phytochem. 2012;1(3):45- 50.
Wang GX, Han J, Zhao LW, Jiang DX, Liu YT, Liu XL. Anthelmintic activity of steroidal saponins from Paris polyphylla. Phytomedicine. 2010;17(14):1102–1105.
DOI:10.1016/j.phymed.2010.04.012.
Just M, Recio MC, Giner RM, CuEllar MJ, Manez S, Bilia AR ET AL. Anti-inflammatory activity of unusual lupane saponins from Bupleurum fruticescen. Planta Med. 1998;64(05):404–407. DOI:10.1055/s-2006-957469.
Sundar S, Joseph LH, Raj TLS. Preliminary phytochemical and antimicrobial investigations of Elytraria acaulis (L.F.) Lindau. Eur. J. Mol. Biol. Biochem. 2015;2(2):71–74.
Jagadeesan K. Studies on the anthelmintic and antioxidant activity of root extracts of Elytraria acaulis. Adv. Anim. Vet. Sci. 2014;2(8):457–463.
DOI:10.14737/journal.aavs/2014/2.8.457.463.
Alves de Almeida AC, de-Faria FM, Dunder RJ, Manzo LPB, Souza-Brito ARM, Luiz-Ferreira A. Recent trends in pharmacological activity of alkaloids in animal colitis: Potential use for inflammatory bowel disease. Evid Based Complement Alternat Med 2017. 2017:1-24.
DOI:10.1155/2017/8528210
Al-shaibani I, Phulan M, Shiekh M. Anthelmintic activity of Fumaria parviflora (Fumariaceae) against gastrointestinal nematodes of sheep. Int. J. Agric. Biol. 2009;11:431–436.
Ravikanth V, Ramesh P, Diwan PV, Venkateswarlu Y. Pyrazole alkaloids from Elytraria acaulis. Biochem. Syst. Ecol. 2001;29(7):753–754.
DOI:10.1016/S0305-1978(00)00109-5
Schroter HB, Neumann D, Katritzky AR, Swinbourne FJ. Withasomnine. A pyrazole alkaloid from Withania somnifera Dun. Tetrahedron 1966;22(8):2895–2897.
DOI:10.1016/S0040-4020(01)99082-9
Santos NE, Carreira ARF, Silva VLM, Braga SS. Natural and biomimetic antitumor pyrazoles, a perspective. Molecules. 2020;25(6):1364.
DOI:10.3390/molecules25061364.
Dragland S, Senoo H, Wake K, Holte K, Blomhoff R. Several culinary and medicinal herbs are important sources of dietary antioxidants. J. Nutr. 2003;133(5):1286–1290.
DOI:10.1093/jn/133.5.1286
Syed M, Fathima A, Johnson M. Spectroscopic studies on Pouzolzia wightii Benn. Int. J. Pharm. Pharm. Sci. 2018;10(3):124–132.
DOI: 10.22159/ijpps.2018v10i3.19336
Donkor S, Larbie C, Komlaga G, Emikpe BO. Phytochemical, antimicrobial, and antioxidant profiles of Duranta erecta L. parts. Biochem. Res. Int. 2019; 2019.
DOI:10.1155/2019/8731595
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