Evaluation of Lactulose Prescribing Pattern in Outpatient Setting
Journal of Pharmaceutical Research International,
Page 33-37
DOI:
10.9734/jpri/2021/v33i331157
Abstract
Aim: This study aims to describe the prescribing pattern of lactulose in the outpatient setting of a public hospital.
Methodology: This is a cross-sectional study that was conducted in Alkharj city. Prescription data were collected retrospectively from electronic medical records in the outpatient setting of the hospital.
Results: A total of 113 patients received lactulose in the outpatient setting of the hospital. Most of them were males (66.37%). Approximately 24% of the patients aged between 30-39 years and about 20.35% of them aged between 20-29. Most of the patients received lactulose for 7 days (70.8%). Most of the prescriptions were written by the Emergency department (84.07%).
Conclusion: Lactulose prescribing was uncommon in the present study. Nevertheless, it is important to use it appropriately to increase its efficacy and safety. The patient should take it as recommended, and the health care professionals should counsel patients about their medications.
Keywords:
- Lactulose
- outpatient
- pattern
- prescribing.
How to Cite
References
Accessed 17 JAN 2021
Available: https://cks.nice.org.uk/constipation#!scenario
De Giorgio R, Ruggeri E, Stanghellini V, Eusebi LH, Bazzoli F, Chiarioni G. Chronic constipation in the elderly: A primer for the gastroenterologist. BMC Gastroenterol. 2015;15:130.
Tvistholm N, Munch L, Danielsen AK. Constipation is casting a shadow over everyday life - a systematic review on older people’s experience of living with constipation. J Clin Nurs. 2017;26:902–14.
Mounsey A, Raleigh M, Wilson A. Management of constipation in older adults. Am Fam Physician. 2015;92:500–4.
Mugie SM, Benninga MA, Di Lorenzo C. Epidemiology of constipation in children and adults: a systematic review. Best Pract Res Clin Gastroenterol. 2011;25:3–18.
NHS. Laxatives; 2021.
Accessed 17 JAN 2021
Available:https://www.nhs.uk/conditions/laxatives/
BPAC. Constipation; 2021.
Accessed 17 JAN 2021.
Available:https://bpac.org.nz/2019/constipation.aspx
Emmanuel A, Mattace-Raso F, Neri MC, Petersen KU, Rey E, Rogers J. Constipation in older people: A consensus statement. Int J Clin Pract. 2017;71.
Schuster BG, Kosar L, Kamrul R. Constipation in older adults: stepwise approach to keep things moving. Can Fam Physician. 2015;61:152–8.
Barish CF, Voss B, Kaelin B. Comparison of preference and safety of powder and liquid lactulose in adult patients with chronic constipation. Clin Exp Gastroenterol. 2010;3:153–158.
Haemmerli UP, Bircher J. Wrong idea, good results (the lactulose story). N Engl J Med. 1969;281(8):441-2.
Dhiman RK, Sawhney MS, Chawla YK, Das G, Ram S, Dilawari JB. Efficacy of lactulose in cirrhotic patients with subclinical hepatic encephalopathy. Dig Dis Sci. 2000;45(8):1549-52.
Wesselius-De Casparis A, Braadbaart S, Bergh-Bohlken GE, Mimica M. Treatment of chronic constipation with lactulose syrup: results of a double-blind study. Gut. 1968;9(1):84-6.
Portalatin M, Winstead N. Medical management of constipation. Clin Colon Rectal Surg. 2012;25(1):12-9.
Healthline.com Lactulose oral solution; 2021.
Accessed 17 JAN 2021.
Available:https://www.healthline.com/health/lactulose-oral-solution#take-as-directed
Aljarari NM, Sharif SI, Jaber AK, Garini AS, Awad AS, Hamed FA. Prescribing patterns of gastrointestinal drugs in private clinics in benghazi-libya. Int J Basic Clin Pharmacol. 2017;6(1):113.
Kolasani BP, Sasidharan P, Divyashanthi CM, Jayabal P, Rajaseharan A. Prescribing pattern of drugs in patients with alcoholic liver disease in a tertiary care teaching hospital. Natl J Physiol Pharm Pharmacol. 2017;7(5):538.
Al Badri AS, AlMuqbali JM, Al Rahbi KY, Al Fannah J, Ahuja A. A study of the paediatric prescriptions at the tertiary care hospital in oman. J Pharmaceut Res. 2020;5(1):17-21.
Aghamohammadi H, Shrestha S, Kavousi S, Milton B. Assessment of prescribing pattern of chemotherapy drugs and monitoring of adverse drug reaction in cancer patients. Int J Pharm Sci Invent. 2019;8:42-51.
Patient Acceptance of Lactulose Varies Between Indian and American Cohorts: Implications for Comparing and Designing Global Hepatic Encephalopathy Trials.
Medscape.com. Lactulose; 2021.
Accessed 17 JAN 2021.
Available:https://reference.medscape.com/drug/enulose-kristalose-lactulose-342016#10.
Mukherjee S, John S. Lactulose. [Updated 2020 Jul 10]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020.
Available:https://www.ncbi.nlm.nih.gov/books/NBK536930/
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