Antibacterial Activity of Datura metel Linn. (TALONG-PUNAY) Fruit Extract
Journal of Pharmaceutical Research International,
Page 96-101
DOI:
10.9734/jpri/2020/v32i2130758
Abstract
Aim: The objective of this study is to determine the phytochemical constituent and antibacterial effect of fruit extract of Datura metel against Staphylococcus aureus and Escherichia coli.
Methods: The extract of the sample underwent a phytochemical screening to identify the secondary metabolites present. Also, an antibacterial test was carried out to test its effectiveness, it was tested by impregnating the respective disc on Mueller-Hilton agar streaked with Staphylococcus aureus and Escherichia coli.
Results: Datura metel fruit extract was observed to have a good antibacterial activity on the two bacteria and this was due to the presence of the phytochemical compounds terpenoids, saponin, alkaloids, steroid, flavonoids, and tannins.
Conclusion: The sample Datura metel fruit extract could be used in the field of pharmaceutical because of its antimicrobial activity and present secondary metabolites.
Keywords:
- Antibacterial activity
- Datura metel Linn
- phytochemical screening
How to Cite
References
The Herb Society of America; 2015. Available:http://www.herbspcietyorg./promplant/dmetel.php
Gufta, Manickam M, Sinha SC, Sinha-Bagchi A, Ray BA. Withanolides of Datura metel. Department of Medical Chemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasti 221 005 India. Journal of Phytochemistry. 1992; 54. ISSN: 2423-2425.
Bratati De. Steroidal compounds from In-vitro regenerated shoots of Datura metel. Fitoterapia. Journal of Chromatographic Science. Department of Botany, Calcutta University, 35 Ballygunge Circular Road, Kolkata 700019, India; 2003.
Siddiq AA, Ali M. Practical pharmaceutical industry. First edition, CBS Publishers and Distributors, New Delhi. 1997;126-131.
Harbone JB. Phytochemical methods- A guide to modern techniques of plant analysis 3rd edition. Chapman and Hall, New York. 1998;1-150.
Guevara BQ. A guide book to plant screening phytochemical and biological. Revised Edition, Espana, Manila University of Santo Tomas Publishing House; 2005.
Saranraj P. Screening of Datura metel leaf extracts against bacterial pathogen. International Journal of Pharmaceutical and Botanical Archive, Department of Microbiology, Annamalai University, Annamali Nagar, Chidambaram – 608 002, Tamil Nadu, India. 2011;2(4). ISSN: 1130-1136.
Anpin Raja RD, Prakash JW, Jeeva S. Antibacterial activity of some medicinal plants used by Kani tribe, southern Western Ghats, Tamilnadu, India. In: Trivedi PC. (ed.) Ethnic tribes and medicinal plans. Jaipur: Pointer Publishers. 2010;28-45.
Koochak H, Nejad SMS, Motamedi H. Preliminary study on the antibacterial activity of some medicinal plants of Khuzestan (Iran). Asian Pacific Journal of Tropical Medicine. 2010;3(3):180-184.
Hilal Tahiya. Comparative study phytochemical screening, antioxidant and antimicrobial capacities of fresh and dry leaves crude extracts of Datura metel. Journal of King Saud University-Science, School of Pharmacy, College of Pharmacy and Nursing, University of Nizwa, P.O. Box 33, Nizwa, Oman. 2014; 26(3). ISSN: 1018-3647.
Akharaiyi FC. Antibacterial, phytochemical and antioxidant activities of Datura metel. International Journal of Pharm Tech Research, Microbiology Department, Federal University of Technology, P.M.B. 704, Akure, Ondo State, Nigeria. 2011; 3(1). ISSN: 09744304.
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