Awareness of Dental Students on the Application of PRF in Dental Practice - A Survey
Journal of Pharmaceutical Research International,
Page 101-113
DOI:
10.9734/jpri/2020/v32i1730673
Abstract
Platelet-rich fibrin (PRF) is a fibrin matrix in which platelet cytokines, growth factors, and cells are trapped and may be released after a certain time and that can serve as a resorbable membrane.
In other words, it is an increased concentration of platelets suspended in a matrix which can serve as a vehicle to carry cells involved in tissue regeneration. This survey aimed at assessing the knowledge and awareness of Platelet-rich fibrin among dental students. The study was done in an online setting among the dental students of the Chennai population. The sample size of 150 participants of the age group 20-23 years, both males and females were selected by a simple random sampling method. Both descriptive (frequency of the responses) and inferential statistics (Chi-square tests) were done and the results were presented in the forms of graphs. According to this survey-based study, it was noted that the majority of participants were comprised of females (67%). It was observed that 87% of the population participated in the study were aware of the term PRF (ie. platelet-rich fibrin) whereas 13% of the population was not aware of the term. The statistical association between gender and the awareness of PRF, its advantages, and components was found to be significant (p<0.05), with females having more awareness than males. Within the limitations of this study, we can conclude that while dental students are aware of PRF they do not have extensive knowledge of its components and its application in various procedures. It was also observed that there was a disparity in awareness between the genders where females were much aware compared to males. We propose to include this knowledge of PRF in the curriculum to ensure increased awareness of PRF among dental students.
Keywords:
- Awareness
- gender
- growth factors
- platelet-rich fibrin
How to Cite
Sriram, K., Ganapathy, D., & Duraisamy, R. (2020). Awareness of Dental Students on the Application of PRF in Dental Practice - A Survey. Journal of Pharmaceutical Research International, 32(17), 101-113. https://doi.org/10.9734/jpri/2020/v32i1730673
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Evaluation of corrosive behavior of four nickel–chromium alloys in artificial saliva by cyclic polarization test:an in vitro study. World Journal of Dentistry. 2017;8(6):477–82.
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Gupta P, Ariga P, Deogade SC. Effect of monopoly-coating agent on the surface roughness of a tissue conditioner subjected to cleansing and disinfection: a contact profilometric study. Contemp Clin Dent. 2018;9(Suppl 1):S122–6.
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Choukroun J, Belveze C, Girard MO, Roche JL, Schoeffler C, Simonpieri A, et al. Sinus-lifts: comment éviter la contamination peropératoire systématique? [Internet]. Vol. 13, Implantodontie. 2004; 131–5.
Available:http://dx.doi.org/10.1016/j.implan.2004.06.005
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Fernández-Delgado N, Hernández-Ramírez P, Forrellat-Barrios M. Platelet functional spectrum: from hemostasis to regenerative medicine. Revista Cubana de Hematología, Inmunología y Hemoterapia. 2012;28(3):200–16.
Mazor Z, Horowitz RA, Del Corso M, Prasad HS, Rohrer MD, Dohan Ehrenfest DM. Sinus floor augmentation with simultaneous implant placement using Choukroun’s platelet-rich fibrin as the sole grafting material: A radiologic and histologic study at 6 months. J Periodontol. 2009;80(12):2056–64.
Toffler M, Toscano N, Holtzclaw D, Corso MD, Ehrenfest DD. Introducing Choukroun’s Platelet Rich Fibrin (PRF) to the reconstructive surgery milieu. J Implant Adv Clin Dent. 2009;1(6):21–30.
Tykhomyrova A. I-PRF and A-PRF as a biological method of treatment and regeneration in dentistry and cosmetology [Internet]. Vol. 08, Dentistry; 2018.
Available:http://dx.doi.org/10.4172/2161-1122-c3-035
Tunalı M, Özdemir H, Küçükodacı Z, Akman S, Yaprak E, Toker H, et al. A novel platelet concentrate: titanium-prepared platelet-rich fibrin. Biomed Res Int. 2014;2014:209548.
Albilia JB, Herrera-Vizcaino C, Weisleder H, Choukroun J, Ghanaati S. Liquid platelet-rich fibrin injections as a treatment adjunct for painful temporomandibular joints: preliminary results. Cranio. 2018;1–13.
Baiomy AA, Edrees M, Al-Ashmawy M. Versatility of injectable platelet rich fibrin versus autologous blood injection in the treatment of chronic recurrent temporomandibular joint dislocation. Egyptian Journal of Oral and Maxillofacial Surgery. 2019;10(2):64–9.
Preeja C, Arun S. Platelet-rich fibrin: Its role in periodontal regeneration. The Saudi Journal for Dental Research. 2014;5(2): 117–22.
Saini K, Chopra P, Sheokand V. Journey of Platelet Concentrates: A Review. Biomedical and Pharmacology Journal. 2020;13(1):185–91.
Dohan DM, Del Corso M, Charrier J-B. Cytotoxicity analyses of Choukroun’s platelet-rich fibrin (PRF) on a wide range of human cells: The answer to a commercial controversy. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology. 2007;5(103):587–93.
Bennett NT, Schultz GS. Growth factors and wound healing: biochemical properties of growth factors and their receptors. Am J Surg. 1993;165(6):728–37.
Mathur A, Bains VK, Gupta V, Jhingran R, Singh GP. Evaluation of intrabony defects treated with platelet-rich fibrin or autogenous bone graft: A comparative analysis [Internet]. Vol. 09, European Journal of Dentistry. 2015;100–8.
Available:http://dx.doi.org/10.4103/1305-7456.149653
Dohan DM, Choukroun J, Diss A, Dohan SL, Dohan AJJ, Mouhyi J, et al. Platelet-rich fibrin (PRF): A second-generation platelet concentrate. Part II: platelet-related biologic features. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;101(3): e45–50.
Li Q, Pan S, Dangaria SJ, Gopinathan G, Kolokythas A, Chu S, et al. Erratum to platelet-rich fibrin promotes periodontal regeneration and enhances alveolar bone augmentation [Internet]. Vol. 2020, BioMed Research International. 2020;1–1.
Available:http://dx.doi.org/10.1155/2020/1794206
Dohan DM, Choukroun J, Diss A, Dohan SL, Dohan AJJ, Mouhyi J, et al. Platelet-Rich Fibrin (PRF): A second-generation platelet concentrate. Part III: leucocyte activation: A new feature for platelet concentrates? Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;101(3): e51–5.
Kawase T, Kamiya M, Kobayashi M, Tanaka T, Okuda K, Wolff LF, et al. The heat-compression technique for the conversion of platelet-rich fibrin preparation to a barrier membrane with a reduced rate of biodegradation. J Biomed Mater Res B Appl Biomater. 2015;103(4): 825–31.
Wu CL, Lee SS, Tsai CH, Lu KH, Zhao JH, Chang YC. Platelet-rich fibrin increases cell attachment, proliferation and collagen-related protein expression of human osteoblasts [Internet]. Vol. 57, Australian Dental Journal. 2012;207–12.
Available:http://dx.doi.org/10.1111/j.1834-7819.2012.01686.x
Chang YC, Zhao JH. Effects of platelet-rich fibrin on human periodontal ligament fibroblasts and application for periodontal infrabony defects. Aust Dent J [Internet]; 2011. Available:https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1834-7819.2011.01362.x
Molly L, Quirynen M, Michiels K, van Steenberghe D. Comparison between jaw bone augmentation by means of a stiff occlusive titanium membrane or an autologous hip graft: A retrospective clinical assessment. Clin Oral Implants Res. 2006;17(5):481–7.
Saluja H, Dehane V, Mahindra U. Platelet-Rich fibrin: A second generation platelet concentrate and a new friend of oral and maxillofacial surgeons. Ann Maxillofac Surg. 2011;1(1):53.
Joseph RV, Sam G, Amol NV. Clinical evaluation of autologous platelet rich fibrin in horizontal alveolar bony defects. J Clin Diagn Res. 2014;8(11):ZC43–7.
Anbu RT, Suresh V, Gounder R, Kannan A. comparison of the efficacy of three different bone regeneration materials: An animal study. Eur J Dent. 2019;13(1):22–8.
Ashok V, Ganapathy D. A geometrical method to classify face forms. J Oral Biol Craniofac Res. 2019;9(3):232–5.
Ganapathy DM, Kannan A, Venugopalan S. Effect of Coated surfaces influencing screw loosening in implants: A Systematic Review and Meta-analysis. World Journal of Dentistry. 2017;8(6):496–502.
Jain AR. Clinical and functional outcomes of implant prostheses in fibula free flaps. World Journal of Dentistry. 2017;8(3):171–6.
Ariga P, Nallaswamy D, Jain AR, Ganapathy DM. Determination of correlation of width of maxillary anterior teeth using extraoral and intraoral factors in indian population: A systematic review. World Journal of Dentistry. 2018;9(1):68–75.
Evaluation of corrosive behavior of four nickel–chromium alloys in artificial saliva by cyclic polarization test:an in vitro study. World Journal of Dentistry. 2017;8(6):477–82.
Ranganathan H, Ganapathy DM, Jain AR. Cervical and incisal marginal discrepancy in ceramic laminate veneering materials: A sem analysis. Contemp Clin Dent. 2017; 8(2):272–8.
Jain ar. Prevalence of partial edentulousness and treatment needs in rural population of south india. world journal of dentistry. 2017;8(3):213–7.
Duraisamy R, Krishnan CS, Ramasubramanian H, Sampathkumar J, Mariappan S, Navarasampatti Sivaprakasam A. Compatibility of nonoriginal abutments with implants: evaluation of microgap at the implant-abutment interface, with original and nonoriginal abutments. Implant Dent. 2019; 28(3):289–95.
Gupta P, Ariga P, Deogade SC. Effect of monopoly-coating agent on the surface roughness of a tissue conditioner subjected to cleansing and disinfection: a contact profilometric study. Contemp Clin Dent. 2018;9(Suppl 1):S122–6.
Varghese SS, Ramesh A, Veeraiyan DN. Blended module-based teaching in biostatistics and research methodology: a retrospective study with postgraduate dental students. J Dent Educ. 2019;83(4): 445–50.
Choukroun J, Belveze C, Girard MO, Roche JL, Schoeffler C, Simonpieri A, et al. Sinus-lifts: comment éviter la contamination peropératoire systématique? [Internet]. Vol. 13, Implantodontie. 2004; 131–5.
Available:http://dx.doi.org/10.1016/j.implan.2004.06.005
Simonpieri A, Choukroun J, Del Corso M, Sammartino G, Dohan Ehrenfest DM. Simultaneous sinus-lift and implantation using microthreaded implants and leukocyte- and platelet-rich fibrin as sole grafting material: A six-year experience. Implant Dent. 2011;20(1):2–12.
Fernández-Delgado N, Hernández-Ramírez P, Forrellat-Barrios M. Platelet functional spectrum: from hemostasis to regenerative medicine. Revista Cubana de Hematología, Inmunología y Hemoterapia. 2012;28(3):200–16.
Mazor Z, Horowitz RA, Del Corso M, Prasad HS, Rohrer MD, Dohan Ehrenfest DM. Sinus floor augmentation with simultaneous implant placement using Choukroun’s platelet-rich fibrin as the sole grafting material: A radiologic and histologic study at 6 months. J Periodontol. 2009;80(12):2056–64.
Toffler M, Toscano N, Holtzclaw D, Corso MD, Ehrenfest DD. Introducing Choukroun’s Platelet Rich Fibrin (PRF) to the reconstructive surgery milieu. J Implant Adv Clin Dent. 2009;1(6):21–30.
Tykhomyrova A. I-PRF and A-PRF as a biological method of treatment and regeneration in dentistry and cosmetology [Internet]. Vol. 08, Dentistry; 2018.
Available:http://dx.doi.org/10.4172/2161-1122-c3-035
Tunalı M, Özdemir H, Küçükodacı Z, Akman S, Yaprak E, Toker H, et al. A novel platelet concentrate: titanium-prepared platelet-rich fibrin. Biomed Res Int. 2014;2014:209548.
Albilia JB, Herrera-Vizcaino C, Weisleder H, Choukroun J, Ghanaati S. Liquid platelet-rich fibrin injections as a treatment adjunct for painful temporomandibular joints: preliminary results. Cranio. 2018;1–13.
Baiomy AA, Edrees M, Al-Ashmawy M. Versatility of injectable platelet rich fibrin versus autologous blood injection in the treatment of chronic recurrent temporomandibular joint dislocation. Egyptian Journal of Oral and Maxillofacial Surgery. 2019;10(2):64–9.
Preeja C, Arun S. Platelet-rich fibrin: Its role in periodontal regeneration. The Saudi Journal for Dental Research. 2014;5(2): 117–22.
Saini K, Chopra P, Sheokand V. Journey of Platelet Concentrates: A Review. Biomedical and Pharmacology Journal. 2020;13(1):185–91.
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