Main Article Content
The solubility of calcium phosphate crystallization in vitro by an deproteinized concoction of Basella rubra plant was investigated by weight reduction assay. Soluble oxalate of the plant are partially removed prior to extraction of plant material. The weight variation and dissolution results reveals that the concoction showed considerable increased activity at the highest concentration used. The results indicate that the calcium phosphate crystal inhibition activity exhibited by the plant material may be due to their calcium phosphate solubilising capacity of phytoconstituents present in them. Regular consumption of an concoction of our plant would be helpful in calculi prophylaxis.
Nirmala S, Saroja G and Gayathri Devi. Antidiabetic activity of Basella rubra and its relationship with the antioxidant property. A British Biotechnology Journal. 2011;1(1):1-9.
Cai-Xia Dong, Kyoko Hayashi, Yusuke Mizukoshi, Jung-Bum Lee. Toshimitsu Hayashi Structures of acidic polysaccharides from Basella rubra L. and their antiviral effects. Carbohydrate Polymers. 2011;84(3):1084-92.
Nisarat Siriwatanametanon, Bernd L, Fiebich, Thomas Efferth, Jose M. Prieto, Michael Heinrich, et al. Traditionally used Thai medicinal plants: In vitro anti-inflammatory, anticancer and antioxidant activities Journal of Ethnopharmacology. 2010;130(2):196–207.
Sandopu Sravan Kumar, Richa Shrivastava and Mausumi Bharadwaj. Fruit extracts of Basella rubra that are rich in bioactives and betalains exhibit antioxidant activity and cytotoxicity against human cervical carcinoma cells. Journal of Functional Foods. 2015;15:509-15.
Shu-Mei Lin, Bo-Hong Lin, Wan-Mei Hsieh, Huey-Jiun Ko, Chi-Dong Liu, Lih-Geeng Chen, Robin YY, Chiou, et al. Structural Identification and Bioactivities of Red-Violet Pigments Present in Basella alba Fruits J. Agric. Food Chem. 2010;58(19): 10364-372.
Besagarahalli Padmanabh Nandini, Mysore Shankar Singh Sudarshana and Nanjaiah Rajashekar. Assessment of antioxidant potentiality of leafy herbs subjecting to different cooking temperatures. International Journal of Chemical and Analytical Science, 2013; 197-200.
Al-Wahsh IA, Wu Y and Liebman M. A comparison of two extraction methods for food oxalate assessment. J Food Res. 2012;1:233-35.
Sweta Bawari, Archana Negisah, Devesh Tewari. Antiurolithiatic activity of Daucus carota, an in vitro study. Pharmacogn J. 2018;10(5):880-884.
Boxi M, Rajesh Y, Raja, Kumar V, Praveen B and Mangamma. Extraction, phytochemical screening and in-vitro evaluation of anti-oxidant properties of Commicarpus chinesis (aqueous leaf extract). Int. J. Pharm. Biosci. 2010;1:537-47.
Rohan Sharadanand phatak, Anup Subhash Hendre, Phytochemical and in vitro anti urolithiatic activity of Kalanchoe pinnata leaves extract. International Journal of Pharmacognosy and Phytochemical Activity. 2015;7(2):275-79.
Chaudhary, Singla SK, Tandon C. In vitro evaluation of Terminalia arjuna on calcium phosphate and calcium oxalate crystallization. Indian Journal of Pharmaceutical Sciences. 2010;7(2):340-45.
Yachi L, Bennis S, Aliat Z. Litholytic activity of some medicinal plants on urinary stones. African Journal of Urology. 2018; 24:197-201.
Agarwal A, Singla S, Gandhi M and Tandon C. Preventive and curative effects of Achyranthes aspera L. extract in experimentally induced nephrolithiasis. Indian J Exp Biol. 2012;50:201-08.
Saha S, Verma RJ. Inhibition of calcium oxalate crystallization in vitro by an extract of Bergenia ciliate. Arab J. Urol. 2013;11: 87-92.