Moringa oleifera Derived Phytochemicals against Shikimate Dehydrogenase of Helicobacter pylori Causing Peptic Ulcer
Journal of Pharmaceutical Research International,
Page 118-121
DOI:
10.9734/jpri/2020/v32i930540
Abstract
Moringa oleifera plant extract is traditionally used to cure Peptic ulcer. It is caused by Helicobacter pylori. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that 9-octadecenoic acid can effectively deactivate the shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism.
Keywords:
- Phytochemical
- Moringa oleifera
- Helicobacter pylori
- peptic ulcer.
How to Cite
Behera, S. S., Suvadarshini, S., Chhotaray, T., Sahoo, A., Satapathy, S., Mohapatra, M., Behera, B., & Pradhan, S. (2020). Moringa oleifera Derived Phytochemicals against Shikimate Dehydrogenase of Helicobacter pylori Causing Peptic Ulcer. Journal of Pharmaceutical Research International, 32(9), 118-121. https://doi.org/10.9734/jpri/2020/v32i930540
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Hussain I, Ullah R, Ullah R, Khurram M, Ullah N, Basee A, Khan F, Khattak M, Zahoor M, Khan J, Khan N. Phytochemical analysis of selected medicinal plant. African Journal of Biotechnology. 2011;10: 7487-7492.
Arulselvan P, Karthivashan G, Fakurazi S. Journal of Chemical and Pharmaceutical Research. 2013;5(7):233-239.
Das D, Das S, Pandey M, Bhattacharyay D. In silico analysis of phytochemicals from Mucuna pruriens (L.) DC against Mycobacterium tuberculosis causing tuberculosis. European Journal of Medicinal Plants; 2020.
Brinda OP, Deepu Mathew, Shylaja MR, Sangeetha Davis P, Anita Cherian K, Valsala PA. Isovaleric acid and avicequinone-C are chikungunya virus resistance principles in Glycosmis pentaphylla (Retz.) Correa. 2019;56(2): 111-121.
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