Moringa oleifera Derived Phytochemicals against Shikimate Dehydrogenase of Helicobacter pylori Causing Peptic Ulcer
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Published
Jun 21, 2020
Page:
118-121
Main Article Content
Sonali Suchismita Behera
School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Seema Suvadarshini
School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Truptimayee Chhotaray
School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Archita Sahoo
School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Subhadarshini Satapathy
School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Manasi Mohapatra
School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Bhagyeswari Behera
School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Srimay Pradhan
School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Abstract
Moringa oleifera plant extract is traditionally used to cure Peptic ulcer. It is caused by Helicobacter pylori. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that 9-octadecenoic acid can effectively deactivate the shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism.
Keywords:
Phytochemical, Moringa oleifera, Helicobacter pylori, peptic ulcer.
Article Details
How to Cite
Behera, S. S., Suvadarshini, S., Chhotaray, T., Sahoo, A., Satapathy, S., Mohapatra, M., Behera, B., & Pradhan, S. (2020). Moringa oleifera Derived Phytochemicals against Shikimate Dehydrogenase of Helicobacter pylori Causing Peptic Ulcer. Journal of Pharmaceutical Research International, 32(9), 118-121. https://doi.org/10.9734/jpri/2020/v32i930540
Section
Original Research Article
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Hussain I, Ullah R, Ullah R, Khurram M, Ullah N, Basee A, Khan F, Khattak M, Zahoor M, Khan J, Khan N. Phytochemical analysis of selected medicinal plant. African Journal of Biotechnology. 2011;10: 7487-7492.
Arulselvan P, Karthivashan G, Fakurazi S. Journal of Chemical and Pharmaceutical Research. 2013;5(7):233-239.
Das D, Das S, Pandey M, Bhattacharyay D. In silico analysis of phytochemicals from Mucuna pruriens (L.) DC against Mycobacterium tuberculosis causing tuberculosis. European Journal of Medicinal Plants; 2020.
Brinda OP, Deepu Mathew, Shylaja MR, Sangeetha Davis P, Anita Cherian K, Valsala PA. Isovaleric acid and avicequinone-C are chikungunya virus resistance principles in Glycosmis pentaphylla (Retz.) Correa. 2019;56(2): 111-121.