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Nigella sativa Derived Phytochemicals against Cough

  • Diptiprajnya Sahoo
  • Minati Nayak
  • Sidhartha Ray
  • Mukundjee Pandey
  • Kalpita Bhatta
  • Sushree Susmita Palei
  • Debasmita Rautaray

Journal of Pharmaceutical Research International, Page 98-101
DOI: 10.9734/jpri/2020/v32i930535
Published: 20 June 2020

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Abstract


Nigella sativa plant extract is traditionally used to cure cough. It is caused by Bordetella pertussis. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that p-cymene can effectively deactivate the adenylate cyclase thereby interrupting the life cycle of the organism.


Keywords:
  • Phytochemicals
  • Nigella sativa
  • Bordetella pertussis
  • cough.
  • Full Article - PDF
  • Review History

How to Cite

Sahoo, D., Nayak, M., Ray, S., Pandey, M., Bhatta, K., Palei, S. S., & Rautaray, D. (2020). Nigella sativa Derived Phytochemicals against Cough. Journal of Pharmaceutical Research International, 32(9), 98-101. https://doi.org/10.9734/jpri/2020/v32i930535
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References

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Hussain I, Ullah R, Ullah R, Khurram M, Ullah N, Basee A, Khan F, Khattak M, Zahoor M, Khan J, Khan N. Phytochemical analysis of selected medicinal plant. African Journal of Biotechnology. 2011;10: 7487-7492.

Arulselvan P, Karthivashan G, Fakurazi S. Journal of Chemical and Pharmaceutical Research. 2013;5(7):233-239.

Das D, Das S, Pandey M, Bhattacharyay D. In silico analysis of phytochemicals from Mucuna pruriens (L.) DC against Mycobacterium tuberculosis causing tuberculosis. European Journal of Medicinal Plants; 2020.

Brinda OP, Mathew D, Shylaja MR, Davis PS, Cherian KA, Valsala PA. Isovaleric acid and avicequinone-C are Chikungunya virus resistance principles in Glycosmis pentaphylla (Retz.) Correa. Journal of Vector Borne Diseases. 2019;56(2):111.
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