Nigella sativa Derived Phytochemicals against Cough
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Published
Jun 20, 2020
Page:
98-101
Main Article Content
Diptiprajnya Sahoo
Centurion University of Technology and Management, Odisha, India.
Minati Nayak
Centurion University of Technology and Management, Odisha, India.
Sidhartha Ray
Centurion University of Technology and Management, Odisha, India.
Mukundjee Pandey
Centurion University of Technology and Management, Odisha, India.
Kalpita Bhatta
Centurion University of Technology and Management, Odisha, India.
Sushree Susmita Palei
Centurion University of Technology and Management, Odisha, India.
Debasmita Rautaray
Centurion University of Technology and Management, Odisha, India.
Abstract
Nigella sativa plant extract is traditionally used to cure cough. It is caused by Bordetella pertussis. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that p-cymene can effectively deactivate the adenylate cyclase thereby interrupting the life cycle of the organism.
Keywords:
Phytochemicals, Nigella sativa, Bordetella pertussis, cough.
Article Details
How to Cite
Sahoo, D., Nayak, M., Ray, S., Pandey, M., Bhatta, K., Palei, S. S., & Rautaray, D. (2020). Nigella sativa Derived Phytochemicals against Cough. Journal of Pharmaceutical Research International, 32(9), 98-101. https://doi.org/10.9734/jpri/2020/v32i930535
Section
Original Research Article
References
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Arulselvan P, Karthivashan G, Fakurazi S. Journal of Chemical and Pharmaceutical Research. 2013;5(7):233-239.
Das D, Das S, Pandey M, Bhattacharyay D. In silico analysis of phytochemicals from Mucuna pruriens (L.) DC against Mycobacterium tuberculosis causing tuberculosis. European Journal of Medicinal Plants; 2020.
Brinda OP, Mathew D, Shylaja MR, Davis PS, Cherian KA, Valsala PA. Isovaleric acid and avicequinone-C are Chikungunya virus resistance principles in Glycosmis pentaphylla (Retz.) Correa. Journal of Vector Borne Diseases. 2019;56(2):111.