Moringa oleifera Derived Phytochemicals against  2-hydroxy-3-oxopropionate Reductase of  Salmonella typhi Causing Typhoid

Sonali Suchismita Behera; Seema Suvadarshini; Ipsita Aparajita Mohapatra; Sonali Dash; Akshaya Kumar Sahoo; Soumyashree Nayak; Meenakshee Mohanty; Punya Prateek Majhi; Srimay Pradhan

doi:10.9734/jpri/2020/v32i930534

Moringa oleifera Derived Phytochemicals against 2-hydroxy-3-oxopropionate Reductase of Salmonella typhi Causing Typhoid

Sonali Suchismita Behera

Seema Suvadarshini

Ipsita Aparajita Mohapatra

Sonali Dash

Akshaya Kumar Sahoo

Soumyashree Nayak

Meenakshee Mohanty

Punya Prateek Majhi

Srimay Pradhan

Journal of Pharmaceutical Research International, Page 94-97
DOI: 10.9734/jpri/2020/v32i930534
Published: 20 June 2020

Abstract

Phytochemicals from Moringa oleifera plant extract can cure Typhoid. It is caused by Salmonella typhi. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that 4,8,12,16-tetramethylheptadecan-4-olide can effectively deactivate the 2-hydroxy-3-oxopropionate reductase enzyme thereby interrupting the life cycle of the organism.

Keywords:

Phytochemical
Moringa oleifera
Salmonella typhi
typhoid.

How to Cite

Behera, S. S., Suvadarshini, S., Mohapatra, I. A., Dash, S., Sahoo, A. K., Nayak, S., Mohanty, M., Majhi, P. P., & Pradhan, S. (2020). Moringa oleifera Derived Phytochemicals against 2-hydroxy-3-oxopropionate Reductase of Salmonella typhi Causing Typhoid. Journal of Pharmaceutical Research International, 32(9), 94-97. https://doi.org/10.9734/jpri/2020/v32i930534

References

Henrich J, Heine S, Norenzayan A. The weirdest people in the world? Behavioral and Brain Sciences. 2010;33(2-3): 61-83.

DOI: 10.1017/S0140525X0999152X

Hussain I, Ullah R, Ullah R, Khurram M, Ullah N, Basee A, Khan F, Khattak M, Zahoor M, Khan J, Khan N. Phytochemical analysis of selected medicinal plant. African Journal of Biotechnology. 2011;10: 7487-7492.

Arulselvan P, Karthivashan G, Fakurazi S. Journal of Chemical and Pharmaceutical Research. 2013;5(7):233-239.

Das D, Das S, Pandey M, Bhattacharyay D. In silico analysis of phytochemicals from Mucuna pruriens (L.) DC against Mycobacterium tuberculosis causing tuberculosis. European Journal of Medicinal Plants; 2020.

Brinda OP, Deepu Mathew, Shylaja MR, Sangeetha Davis P, Anita Cherian K, Valsala PA. Isovaleric acid and avicequinone-C are chikungunya virus resistance principles in Glycosmis pentaphylla (Retz.) Correa. 2019;56(2): 111-121.

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