Pavonia odorata Derived Phytochemicals against Entamoeba histolytica Causing Dysentery

Main Article Content

Jogesh Kumar Nayak
Suraj Kumar Sahu
Sitaram Swain
Dipankar Bhattacharyay
Mukundjee Pandey

Abstract

Phytochemicals from Pavonia odorata plant extract are traditionally used to cure Dysentery. It is caused by Entamoeba histolytica. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that palmitic acid can effectively deactivate the Alcohol dehydrogenase enzyme thereby interrupting the life cycle of the organism.

Keywords:
Phytochemical, Pavonia odorata, Entamoeba histolytica

Article Details

How to Cite
Nayak, J. K., Sahu, S. K., Swain, S., Bhattacharyay, D., & Pandey, M. (2020). Pavonia odorata Derived Phytochemicals against Entamoeba histolytica Causing Dysentery. Journal of Pharmaceutical Research International, 32(8), 125-128. https://doi.org/10.9734/jpri/2020/v32i830531
Section
Original Research Article

References

Henrich J, Heine S, Norenzayan A. The weirdest people in the world? Behavioral and Brain Sciences. 2010;33(2-3):61-83. DOI: 10.1017/S0140525X0999152X

Hussain I, Ullah R, Ullah R, Khurram M, Ullah N, Basee A, Khan F, Khattak M, Zahoor M, Khan J, Khan N. Phytochemical analysis of selected medicinal plant. African Journal of Biotechnology. 2011;10: 7487-7492.

Arulselvan P, Karthivashan G, Fakurazi S. Journal of Chemical and Pharmaceutical Research. 2013;5(7):233-239.

Das D, Das S, Pandey M, Bhattacharyay D. In silico analysis of phytochemicals from Mucuna pruriens (L.) DC against Mycobacterium tuberculosis causing tuberculosis. European Journal of Medicinal Plants; 2020.

Brinda OP, Mathew D, Shylaja MR, Davis PS, Cherian KA, Valsala PA. Isovaleric acid and avicequinone-C are Chikungunya virus resistance principles in Glycosmis pentaphylla (Retz.) Correa. Journal of Vector Borne Diseases. 2019; 56(2):111.