Buddleja asiatica Lour. Derived Phytochemicals against Staphylococcus aureus Causing Skin Diseases

Main Article Content

Sasmita Patra
Sarthak Siddhant Mishra
Manaranjan Behera
Ruchi Samparna Sahoo
Swetanginee Gouda
Sushree Susmita Palei
Gyanranjan Mahalik

Abstract

Phytochemicals from Buddleja asiatica plant extract are traditionally used to cure skin diseases. It is caused by Staphylococcus aureus. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that lignoceric acid can effectively deactivate the L-lactate dehydrogenase enzyme thereby interrupting the life cycle of the organism.

Keywords:
Buddleja asiatica, phytochemical, Staphylococcus aureus, skin diseases

Article Details

How to Cite
Patra, S., Mishra, S. S., Behera, M., Sahoo, R. S., Gouda, S., Palei, S. S., & Mahalik, G. (2020). Buddleja asiatica Lour. Derived Phytochemicals against Staphylococcus aureus Causing Skin Diseases. Journal of Pharmaceutical Research International, 32(8), 117-120. https://doi.org/10.9734/jpri/2020/v32i830529
Section
Original Research Article

References

Henrich J, Heine S, Norenzayan A. The weirdest people in the world? Behavioral and Brain Sciences. 2010;33(2-3):61-83. DOI: 10.1017/S0140525X0999152X

Hussain I, Ullah R, Ullah R, Khurram M, Ullah N, Basee A, Khan F, Khattak M, Zahoor M, Khan J, Khan N. Phytochemical analysis of selected medicinal plant. African Journal of Biotechnology. 2011;10: 7487-7492.

Arulselvan P, Karthivashan G, Fakurazi S. Journal of Chemical and Pharmaceutical Research. 2013;5(7):233-239.

Das D, Das S, Pandey M, Bhattacharyay D. In silico analysis of phytochemicals from Mucuna pruriens (L.) DC against Mycobacterium tuberculosis causing tuberculosis. European Journal of Medicinal Plants; 2020.

Brinda OP, Mathew D, Shylaja MR, Davis PS, Cherian KA, Valsala PA. Isovaleric acid and avicequinone-C are Chikungunya virus resistance principles in Glycosmis pentaphylla (Retz.) Correa. Journal of Vector Borne Diseases. 2019;56(2):111.