Bixa orellana L. Derived Phytochemicals against Alcohol Dehydrogenase of Escherichia coli

Main Article Content

Sonali Parida
Anindita Jena
Jogesh Kumar Nayak
Sonali Dash
Dipankar Bhattacharyay


Phytochemicals from Bixa orellana L. plant extract are traditionally used to cure Jaundice. It is caused by Escherichia coli. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of         -CDOCKER energy and -CDOCKER interaction energy” suggested that benzoic acid can effectively deactivate the alcohol dehydrogenase enzyme thereby interrupting the life cycle of the organism.

Phytochemical, Bixa orellana L., Escherichia coli

Article Details

How to Cite
Parida, S., Jena, A., Nayak, J. K., Dash, S., & Bhattacharyay, D. (2020). Bixa orellana L. Derived Phytochemicals against Alcohol Dehydrogenase of Escherichia coli. Journal of Pharmaceutical Research International, 32(8), 101-104.
Original Research Article


Henrich J, Heine S, Norenzayan A. The weirdest people in the world? Behavioral and Brain Sciences. 2010;33(2-3):61-83. DOI: 10.1017/S0140525X0999152X

Hussain I, Ullah R, Ullah R, Khurram M, Ullah N, Basee A, Khan F, Khattak M, Zahoor M, Khan J, Khan N. Phytochemical analysis of selected medicinal plant. African Journal of Biotechnology. 2011;10: 7487-7492.

Arulselvan P, Karthivashan G, Fakurazi S. Journal of Chemical and Pharmaceutical Research. 2013;5(7):233-239.

Das D, Das S, Pandey M, Bhattacharyay D. In silico analysis of phytochemicals from Mucuna pruriens (L.) DC against Mycobacterium tuberculosis causing tuberculosis. European Journal of Medicinal Plants; 2020.

Brinda OP, Mathew D, Shylaja MR, Davis PS, Cherian KA, Valsala PA. Isovaleric acid and avicequinone-C are chikungunya virus resistance principles in Glycosmis pentaphylla (Retz.) Correa. Journal of Vector Borne Diseases. 2019; 56(2):111.