Michelia champaca Derived Phytochemicals against Skin Disease
Journal of Pharmaceutical Research International,
Page 144-147
DOI:
10.9734/jpri/2020/v32i630511
Abstract
Phytochemicals from Michelia champaca plant extract can cure skin disease. Skin disease can be caused by many reasons. Infections due to Staphylococcus aureus is one of the main reasons for skin disease. This objective of the study is to identify the phytochemical of Michelia champaca capable of curing skin diseases. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Magnoflorine can effectively deactivate thymidylate synthase thereby interrupting the life cycle of the organism.
Keywords:
- Phytochemical
- Michelia champaca
- Staphylococcus aureus
How to Cite
References
DOI: 10.1017/S0140525X0999152X
Hussain I, Ullah R, Ullah R, Khurram M, Ullah N, Basee A, Khan F, Khattak M, Zahoor M, Khan J, Khan N. Phytochemical analysis of selected medicinal plant. African Journal of Biotechnology. 2011;10:7487-7492.
Arulselvan P, Karthivashan G, Fakurazi S. Journal of Chemical and Pharmaceutical Research. 2013;5(7):233-239.
Balurgi VC, Rojatkar SR, Pujar PP, Patwardhan BK, Nagasampagi BA. Isolation of parthenolide from the leaves of Michelia champaca Linn. Indian Drugs. 1997;34(7).
Kapoor S, Jaggi RK. Chemical studies on flowers of Michelia champaca. Indian Journal of Pharmaceutical Sciences. 2004;66(4):403.
Banerjee SK, Chakravarti RN, Fales HM. Liriodenine from Michelia champaca. Bulletin of the Calcutta School of Tropical Medicine. 1964;12:23-24.
Sethi VK, Thappa RK, Dhar KL, Atal CK. Constituents of Michelia champaca and Lewis acid catalysed transformations of parthenolide into guaianolides. Planta Medica. 1984;50(04):364-364.
Yang TH, Hsiao CY. Studies on the alkaloids of magnoliaceous plants. 36, alkaloids of Michelia champaca Linn. Yakugakuzasshi: Journal of the Pharmaceutical Society of Japan. 1963;83: 216-218.
Das D, Das S, Pandey M, Bhattacharyay D. In silico analysis of phytochemicals from Mucuna pruriens (L.) DC against Mycobacterium tuberculosis causing tuberculosis. European Journal of Medicinal Plants; 2020.
Brinda OP, Mathew D, Shylaja MR, Davis PS, Cherian KA, Valsala PA. Isovaleric acid and avicequinone-C are chikungunya virus resistance principles in Glycosmis pentaphylla (Retz.) Correa. Journal of Vector Borne Diseases. 2019;56(2): 111.
-
Abstract View: 565 times
PDF Download: 193 times
