Capsicum Derived Phytochemicals against Shikimate Dehydrogenase of Haemophilus influenza causing Bronchitis
Journal of Pharmaceutical Research International,
Page 128-131
DOI:
10.9734/jpri/2020/v32i630507
Abstract
Phytochemicals from Capsicum plant extract are traditionally used to cure Bronchitis. It is caused by Haemophilus influenzae. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Apigenin can effectively deactivate the Shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism.
Keywords:
- Phytochemical
- capsicum
- Haemophilus influenza
How to Cite
Hota, D. K., Nayak, D., Swain, S., & Bhattacharyay, D. (2020). Capsicum Derived Phytochemicals against Shikimate Dehydrogenase of Haemophilus influenza causing Bronchitis. Journal of Pharmaceutical Research International, 32(6), 128-131. https://doi.org/10.9734/jpri/2020/v32i630507
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Arulselvan P, Karthivashan G, Fakurazi S. Journal of Chemical and Pharmaceutical Research. 2013;5(7):233-239.
Lengauer T, Rarey M. Computational methods for biomolecular docking. Current Opinion in Structural Biology. 1996;6(3): 402–6.
Das D, Das S, Pandey M, Bhattacharyay D. In silico analysis of phytochemicals from Mucuna pruriens (L.) DC against Mycobacterium tuberculosis causing tuberculosis. European Journal of Medicinal Plants; 2020.
Brinda OP, Mathew D, Shylaja MR, Davis PS, Cherian KA, Valsala PA. Isovaleric acid and avicequinone-C are chikungunya virus resistance principles in Glycosmis pentaphylla (Retz.) Correa. Journal of Vector Borne Diseases. 2019; 56(2):111.
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