Antioxidant Nano Phlorotannin Powder from Brown Algae Sargassum serratum: Spray Drying, Antioxidant Activities, Physic-Chemical Characterization

Main Article Content

Dang Xuan Cuong


Introduction: Phlorotannins are bioactive-value polymers existing in brown algae and useful for pharmaceutics and functional food. Therefore, the study focused on the spray drying conditions survey, the evaluation of antioxidant activities, and physico-chemical characterization of antioxidant nano phlorotannin powder prepared from brown algae Sargassum serratum.

Methods: To survey the effect of spray drying conditions (carriers, carrier-to-solution ratio, compressed air pressure, liquid feed speed, inlet air temperature) on antioxidant activities (total antioxidant, reducing power, DPPH free radical scavenging), and physico-chemical (solubility degree, moisture, particle morphology, and bulk density) of antioxidant phlorotannin powder from brown algae Sargassum serratum commonly growing in the Vietnam sea area.

Results: The optimum spray drying condition consisted of the carrier-to-solution ratio of 10%, compressed air pressure of 0.8 bar, the liquid feed speed of 10 ml min-1, and the inlet temperature of 110°C. At the optimization condition, the antioxidant activity of phlorotannin powder possessed total antioxidant (4.347 ± 0.018 g ascorbic acid equivalent 100-1 g DP), reducing power activity (9.390 ± 0.024 g FeSO4 equivalent 100-1 g DP), DPPH free radical scavenging activity ((70.02 ± 0.26)%), physico-chemical of antioxidant phlorotannin powder consisting of moisture content (5 ± 0.5%), phlorotannin content (2.268 ± 0.010 g phloroglucinol equivalent 100-1 g DP), solubility degree (100%), and bulk density (<1 g/ml). Phlorotannin content and antioxidant activities were affected by the spray drying condition (p < 0.05) and a strong correlation to each other (R2 > 0.9). Antioxidant phlorotannin particles possessed nanometer size and the morphology of irregular and microspheres.

Conclusion: Antioxidant nano phlorotannin powder could be usefulas functional food and pharmaceuticals.

Antioxidants, phlorotannin, powder, seaweed, spray drying

Article Details

How to Cite
Cuong, D. X. (2020). Antioxidant Nano Phlorotannin Powder from Brown Algae Sargassum serratum: Spray Drying, Antioxidant Activities, Physic-Chemical Characterization. Journal of Pharmaceutical Research International, 32(9), 71-85.
Original Research Article


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