The Effect of Root Canal Irrigant Solutions and Different Filling Periods on Microleakage of Resin Composite (An In vitro Study)
Journal of Pharmaceutical Research International,
Aims: Chemical irrigants used in endodontic treatments, may cause changes in the composition of the dentin surface and affect its interaction with resin composite. Sodium hypochlorite and chlorhexidine gluconate (CHX) are common root canal Irrigant solutions. Sodium hypochlorite and CHX have a potential of antimicrobial activity but CHX is less toxic compared with sodium hypochlorite. So CHX may be considered as a good alternative for sodium hypochlorite irrigant solution. The aim of this study was to compare the effects of different root canal irrigation solutions subsequent to endodontic therapy on microleakage of clearfil S3 bond and Z250 resin composite restoration after applying immediate or delayed periods.
Materials and Methods: This in-vitro study was done on 80 single-rooted human maxillary intact premolar teeth. After disinfection, access cavity preparation was done. Teeth were randomly divided into 8 equal groups according to canal irrigation type(0.2% chlorhexidine, 2.5% sodium hypochlorite, saline normal) and time of restoration by Clearfil S3 Bond (Kuraray, Japan) and Z250 (3M, USA) resin composite (immediately, one week later) and compared with control group. After thermocycling, dye penetration was done and microleakage was recorded. Data were analyzed using chi-square, Kruskal–Wallis and Kolmogorov-Smirnov statistical tests.
Results: Microleakage rate in all groups of canal irrigants with immediately or after a week restoration with resin composite were not statistically significant (p> 0.05). The microleakage rate in immediately and after a week resin composite restoration filling with using different canal irrigants had a statistically significant difference (p < 0.0001).
Conclusion: The Microleakage rate was not significantly different between immediate and after one week of canal irrigation and composite resin filling. Using 0.2% chlorhexidine and 2.5% sodium hypochlorite irrigants reduce significantly microleakage rate compared to saline.
- Canal irrigants
- resin composite
- self-etch adhesive
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