Journal of Pharmaceutical Research International 2020-05-25T07:41:12+00:00 Journal of Pharmaceutical Research International Open Journal Systems <p style="text-align: justify;"><strong>Journal of Pharmaceutical Research International (ISSN:&nbsp;2456-9119)</strong> is dedicated to publish&nbsp;high quality papers (<a href="/index.php/JPRI/general-guideline-for-authors">Click here for Types of paper</a>)&nbsp;in all areas of pharmaceutical Science including pharmaceutical drugs, community pharmacy, hospital pharmacy, clinical pharmacy, compounding pharmacy, consultant pharmacy, internet pharmacy, veterinary pharmacy, nuclear pharmacy, military pharmacy, pharmacy informatics, pharmaceutics, medicinal chemistry, pharmacognosy, pharmacotherapy, pharmacodynamics, pharmacokinetics, clinical pharmacology, neuropharmacology, psychopharmacology, pharmacogenetics, pharmacogenomics, pharmacoepidemiology, toxicology, theoretical pharmacology, posology, pharmacognosy, behavioral pharmacology, environmental pharmacology, medicine development and safety testing, drug legislation and safety, pharmaceutical microbiology, pharmaceutical molecular biology, pharmaceutical biotechnology.&nbsp;The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer reviewed, open access INTERNATIONAL journal.</p> Use of Enoxaparin in Obstetrics and Gynecology Department 2020-05-25T07:19:35+00:00 Nehad J. Ahmed <p><strong>Aims: </strong>This study aims to demonstrate the use of enoxaparin in obstetrics and gynecology department in Alkharj.</p> <p><strong>Methodology</strong><strong>:</strong> This is a retrospective study was conducted in a public hospital in Alkharj city. The outpatient prescriptions were reviewed to evaluate the prescription patterns&nbsp;of enoxaparin. The data were collected and analyzed using Excel software, the descriptive data were represented by frequencies and percentages.</p> <p><strong>Results</strong><strong>:</strong> About 86.32% of the prescriptions contain enoxaparin syringe were prescribed for female patients. The majority of enoxaparin prescriptions were from obstetrics &amp; gynecology department (79.48%).Moreover, the majority of enoxaparin prescriptions were prescribed by consultants (62.39%).</p> <p><strong>Conclusion</strong><strong>:</strong> The result of this study show that enoxaparin was prescribed commonly in the obstetrics and gynecology department for female patients because of its efficacy and safety profile. Enoxaparin is safer than other anticoagulants but still could cause many adverse effects so it is important to increase the health care professional awareness about its use.</p> 2020-05-25T00:00:00+00:00 ##submission.copyrightStatement## Incidence of Candida Species Infections in a Military Hospital in Al-Kharj, Saudi Arabia 2020-05-25T07:26:39+00:00 Nehad J. Ahmed <p><strong>Aim: </strong>The present study aims to demonstrate the incidence of&nbsp;<em>Candida</em>&nbsp;species associated with infections in a Military hospital in Alkharj.</p> <p><strong>Methodology: </strong>This is a retrospective study that was conducted to assess the prevalence of&nbsp;<em>Candida</em>&nbsp;species in a Military hospital in Alkharj – Saudi Arabia. The isolates from various clinical specimens in 2018 and 2019 were studied.</p> <p><strong>Results: </strong>The percentage of candida species in the 2 years was 6.21% of isolates. The <em>Candida albicans</em> were 40.87% of the total <em>Candida </em>isolates. The majority of <em>Candida</em>&nbsp;species cultures were collected from wound/pus/skin or vagina and to lesser extent urine and lower respiratory tract.</p> <p><strong>Conclusion</strong><strong>:</strong> <em>Candida </em>species are now common pathogens that cause infections specially in the gastrointestinal tract, vagina and at surgical site. It sometimes may lead to high morbidity and mortality rate. It is important to know the resistance rate for the fungi and it is important to start the implementation of antifungal treatment programs.</p> 2020-05-25T00:00:00+00:00 ##submission.copyrightStatement## Effect of a Period of Magnesium Supplementation on Muscle Strength and Resistance of Bodybuilders 2020-05-25T07:31:15+00:00 Seyyed Mehdi Razavi Dehkordi <p><strong>Objective</strong><strong>:</strong> The purpose of this study is to determine the effect of magnesium supplements on the muscular strength of active men.</p> <p><strong>Materials and Methods:</strong> Samples were matched into two groups. Magnesium supplements (containing 47 mg of calcium and 250 mg of magnesium oxide produced by al-Hawi Company) were given to the experimental group and the placebo that was completely similar to the supplements for the control group. The tablets are given to every other subject individually and they performed strength training. Supplements were ingested before strength training in the gym and the supplements were consumed with a glass of water. The statistical population of the study included male bodybuilders’ athletes who are regularly excising three days a week in Shahre Kord sports clubs. 40 subjects were selected from people who were interested to participate in the research. After selecting the samples, they are randomly divided into two groups A and B (double-blind method). The strength of the athletes was measured by the CPR machine based on the 1-RM and their resistance by more repetition of bench press with a standard device using 1-RM by 0.5 Kg in the gym.</p> <p><strong>Results</strong><strong>:</strong> The results of Wilks' lambda test showed that there is a significant difference between the experimental and control groups in one of the measurements related to arms muscle strength and chest muscle strength, while there is no a significant difference between the two groups in measurements related to muscle strength and resistance of the upper body, which means that magnesium supplementation for 8 weeks has had a significant effect on the strength of the hands and chest muscles of the bodybuilders ‘athlete.</p> <p><strong>Conclusion</strong><strong>:</strong> Magnesium supplementation can affect the strength of upper body’s muscles of men.</p> 2020-05-25T00:00:00+00:00 ##submission.copyrightStatement## The Adverse Effect Reporting for the Most Commonly Used Antibiotics 2020-05-25T07:41:12+00:00 Nehad J. Ahmed Mohammed I. Fouda Dina I. Fouda Ahmed I. Foudah <p><strong>Aim:</strong> Antibiotics save lives, but the excess use of antibiotics leads to more side effects. Patients benefit from medications but also complain about their adverse effects. This study aims to explore the reports of the adverse effects for the most commonly used antibiotics in Saudi Arabia.</p> <p><strong>Methodology:</strong> The Data regarding the adverse events reports were collected from The National Pharmacovigilance Center in Saudi Arabia. The data include the major allergic reactions and gastrointestinal side effects for the most commonly used antibiotic classes.</p> <p><strong>Results:</strong> The total number of allergic and gastrointestinal adverse effects in 2017 and 2018 for the included antibiotic drugs is 583 reports. The majority of the reports were for penicillin antibiotics (39.96) particularly Amoxicillin/Clavunate.</p> <p><strong>Conclusion:</strong> The most common adverse effects of antibiotics are allergic and gastrointestinal effects. It is important to report any adverse drug reactions either by health care providers or patients to the Saudi Pharmacovigilance Center.</p> 2020-05-25T00:00:00+00:00 ##submission.copyrightStatement##