Comparison of the Effect of Pregabaline and Diclofenac Suppository on Pain Relief after Elective Cesarean Section

Main Article Content

Asadollah Shakeri
Maryam Razavi
Zeinab Mirkahnuj

Abstract

Introduction: Cesarean section is one of the most common major surgeries performed worldwide. Considering the importance of post-cesarean pain, finding a drug that can provide the patient with the least amount of complications can make the patient feel the least pain and most relaxation. The aim of this study was to compare the effect of pregabaline and diclofenac suppository on pain relief after elective cesarean section with spinal anesthesia.

Methods: This study was performed in 2016 on 100 women admitted to Ali Ibn Abi Talib Hospital due to elective cesarean section. Patients were divided into two groups of 100mg rectal diclofenac half an hour before surgery and 300mg pre-gabbaline group. Data were analyzed using SPSS software. Probability level lower than 0.05 was considered significant.

Results: The mean score of after surgery pain at 6 and 12 hours after surgery in the diclofenac group was significantly lower than in the pregabaline group, but at 18 and 24 hours, the difference between the two groups was not statistically significant. The mean dose of pethidine used in the diclofenac group was significantly lower than the pregabaline group. Maternal satisfaction was significantly higher in the diclofenac group.

Conclusion: According to the results of this study, diclofenac has a stronger antinociceptive effect than pregabalin.

Keywords:
Cesarean section, diclofenac, pregabalin.

Article Details

How to Cite
Shakeri, A., Razavi, M., & Mirkahnuj, Z. (2019). Comparison of the Effect of Pregabaline and Diclofenac Suppository on Pain Relief after Elective Cesarean Section. Journal of Pharmaceutical Research International, 31(6), 1-6. https://doi.org/10.9734/jpri/2019/v31i630355
Section
Original Research Article

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